Applications of DNA microarrays in microbial systems

被引：132

作者：

Ye, RW ^{[1
]}

Wang, T ^{[1
]}

Bedzyk, L ^{[1
]}

Croker, KM ^{[1
]}

机构：

[1] Dupont Co Inc, Cent Res & Dev, DuPont Expt Stn, Wilmington, DE 19880 USA

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2001年 / 47卷 / 03期

关键词：

DNA microarrays; microbial systems; genome; bacteria;

D O I：

10.1016/S0167-7012(01)00308-6

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

DNA microarray technology allows a parallel analysis of RNA abundance and DNA homology for thousands of genes in a single experiment. Over the past few years, this powerful technology has been used to explore transcriptional profiles and genome differences for a variety of microorganisms. greatly facilitating our understanding of microbial metabolism. With the increasing availability of complete microbial genomes. DNA microarrays are becoming a common tool in many areas of microbial research, including microbial physiology, pathogenesis, epidemiology, ecology, phylogeny, pathway engineering and fermentation optimization. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：257 / 272

页数：16

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