Size dependent magnetic hyperthermia of octahedral Fe3O4 nanoparticles

被引:55
|
作者
Lv, Y. [1 ,2 ]
Yang, Y. [1 ]
Fang, J. [1 ]
Zhang, H. [1 ]
Peng, E. [1 ]
Liu, X. [1 ,3 ]
Xiao, W. [1 ]
Ding, J. [1 ]
机构
[1] Natl Univ Singapore, Dept Mat Sci & Engn, Singapore 117574, Singapore
[2] Natl Univ Singapore, NUS Grad Sch Integrat Sci & Engn, Singapore 117456, Singapore
[3] NW Univ Xian, Sch Chem Engn, Shaanxi Key Lab Degradable Biomed Mat, Xian 710069, Peoples R China
关键词
IRON-OXIDE NANOCUBES; SURFACE; ENHANCEMENT; ABSORPTION; PARTICLES; SHELL; CORE;
D O I
10.1039/c5ra12558h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Magnetic nanoparticle hyperthermia is promising as a cancer therapeutic treatment. Shape and size are two crucial factors for the magnetic hyperthermia performance of nanoparticles. In this work, octahedral Fe3O4 nanoparticles with different sizes are successfully synthesized and their magnetic hyperthermia performances are investigated systematically in a gel suspension. The results suggest a wide size range (43-98 nm) for high SAR values (up to 2629 W g(-1)). The SAR values are verified by hysteresis loss measured in the gel suspension. This study demonstrates that octahedral Fe3O4 nanoparticles can serve as an excellent thermal seed for high performance magnetic hyperthermia cancer treatment.
引用
收藏
页码:76764 / 76771
页数:8
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