Liquid Sensor based Bio-Chip for DNA Analysis of Cancer using Photonic Crystal

被引：1

作者：

Patil, Harshada ^{[1
]}

Nischita, R. ^{[2
]}

Indumathi, T. S. ^{[3
]}

Sharan, Preeta ^{[2
]}

机构：

[1] VIT, Dept ECE, Bangalore, Karnataka, India

[2] Oxford Coll Engn, Dept ECE, Bangalore, Karnataka, India

[3] VTU Ctr Adv Technol, Muddenahalli, India

来源：

INTERNATIONAL CONFERENCE ON OPTICAL AND PHOTONIC ENGINEERING (ICOPEN 2015) | 2015年 / 9524卷

关键词：

Photonic Crystals; Refractive Index; Hexagonal Ring Resonator; FDTD; DNA;

D O I：

10.1117/12.2189606

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Silicon photonics is poised to revolutionize bio-sensing applications, specifically in medical diagnostics. The need for cost effective and reliable bio-sensors in medical applications is an ever growing and everlasting one. In this synopsis we have designed a 2-D hexagonal photonic crystal ring resonator based bio-sensor that is able to detect lung cancer from blood. Simulation and analysis has been done for normal DNA and the cancer affected DNA in blood. The intensity level of transmission spectrum has been observed. Finite Difference Time Domain (FDTD) method is used for analysis. MEEP (MIT Electromagnetic Equation Propagation) tool and RSOFT Photonic Suite CAD tool are used designing the photonic crystal sensor. The results show that for small changes in the refractive index of the input samples there is a significant shift in wavelength and amplitude. Thus the sensor is highly sensitive for change in refractive index and hence differentiating normal and cancer affected DNA.

引用

页数：6

共 50 条

[1] 2-D Photonic Crystal based Bio-chip for DNA Analysis of Breast Cancer
Nischita, R.
Gudagunti, Fleming Dackson
Sharan, Preeta
Srinivas, T.
2015 INTERNATIONAL CONFERENCE ON PERVASIVE COMPUTING (ICPC), 2015,
[2] Designing of MO-SPR Bio-chip with Photonic Crystal
Otipka, P.
Vlcek, J.
Lesnak, M.
20TH SLOVAK-CZECH-POLISH OPTICAL CONFERENCE ON WAVE AND QUANTUM ASPECTS OF CONTEMPORARY OPTICS, 2016, 10142
[3] Novel Photonic Bio-Chip Sensor Based on Strained Graphene Sheets for Blood Cell Sorting
Ghasemi, Fatemeh
Razi, Sepehr
MOLECULES, 2021, 26 (18):
[4] Automated Cervical Cancer Detection using Photonic Crystal based Bio-Sensor
Nithin, S.
Sharma, Poonam
Vivek, M.
Sharan, Preeta
2015 IEEE INTERNATIONAL ADVANCE COMPUTING CONFERENCE (IACC), 2015, : 1174 - 1178
[5] Spectral Analysis of Photonic crystal based Bio-Sensor using AdaBoost Algorithm
Sriram, G.
Vivek, M.
Roy, Sandeep Kumar
Sharan, Preeta
2015 INTERNATIONAL CONFERENCE ON COMMUNICATIONS AND SIGNAL PROCESSING (ICCSP), 2015, : 1806 - 1810
[6] Photonic Crystal Based Bio-Sensor Detection in Cancer Cell Using FDTD Method
Sharma, Varsha
Kalyani, Vijay Laxmi
Upadhyay, Shivam
2017 8TH INTERNATIONAL CONFERENCE ON COMPUTING, COMMUNICATION AND NETWORKING TECHNOLOGIES (ICCCNT), 2017,
[7] An Analysis of Quality Factor for Different Bio-analytes by Using Photonic Crystal Based Sensor
Sharma, Poonam
Gudagunti, Fleming Dackson
Sharan, Preeta
2014 INTERNATIONAL CONFERENCE ON ADVANCED COMMUNICATION CONTROL AND COMPUTING TECHNOLOGIES (ICACCCT), 2014, : 924 - 928
[8] Integrating molecular dynamics for DNA bio-chip fabrication and hybridization automation
Zhang, MJ
Pianetta, PA
Tarn, TJ
2005 IEEE/ASME INTERNATIONAL CONFERENCE ON ADVANCED INTELLIGENT MECHATRONICS, VOLS 1 AND 2, 2005, : 25 - 30
[9] Photonic Crystal based Liquid Sensor: A Theoretical Analysis for Formalin Detection
Arif, Md Faizul Huq
Hossain, Mohammad Mobarak
Rahman, Md Mahbubur
Kumar, Mithun P. K.
Khaled, Shah Mostafa
2018 JOINT 7TH INTERNATIONAL CONFERENCE ON INFORMATICS, ELECTRONICS & VISION (ICIEV) AND 2018 2ND INTERNATIONAL CONFERENCE ON IMAGING, VISION & PATTERN RECOGNITION (ICIVPR), 2018, : 295 - 299
[10] Classifying Bio-Chip Data using an Ant Colony System Algorithm
Lee, Minsoo
Kim, Yearn Jeong
Kim, Yun-mi
Cheong, Sujeung
Song, Sookyung
PROCEEDINGS OF WORLD ACADEMY OF SCIENCE, ENGINEERING AND TECHNOLOGY, VOL 14, 2006, 14 : 201 - 205

← 1 2 3 4 5 →