In vitro activity of fosfomycin against extended-spectrum-β-lactamase-producing Escherichia coli and Klebsiella pneumoniae:: Comparison of susceptibility testing procedures

被引：95

作者：

de Cueto, M ^{[1
]}

López, L ^{[1
]}

Hernández, JR ^{[1
]}

Morillo, C ^{[1
]}

Pascual, A ^{[1
]}

机构：

[1] Univ Seville, Hosp Univ Virgen Macarena, Fac Med, Dept Microbiol, Seville 41009, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 01期

关键词：

D O I：

10.1128/AAC.50.1.368-370.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The agar dilution, broth microdilution, and disk diffusion methods were compared to determine the in vitro susceptibility of 428 extended-spectrum-p-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae to fosfomycin. Fosfomycin showed very high activity against all ESBL-producing strains. Excellent agreement between the three susceptibility methods was found for E. coli, whereas marked discrepancies were observed for K. pneumoniae.

引用

页码：368 / 370

页数：3

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