Beating the heat: A translation factor and an RNA mobilize the heat shock transcription factor HSF1

被引:13
|
作者
Kugel, JF [1 ]
Goodrich, JA [1 ]
机构
[1] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80309 USA
关键词
D O I
10.1016/j.molcel.2006.04.003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cells respond to stress via orchestrated modifications in gene expression; in a recent publication in Nature, Shamovsky et al. (2006) report that an RNA and a translation factor regulate the activity of a transcriptional activator essential to the mammalian heat shock response.
引用
收藏
页码:153 / 154
页数:2
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