Successful Maternal and Fetal Outcome in a Kidney Transplant Patient with Everolimus Exposure Throughout Pregnancy: A Case Report

被引：25
|
作者：
Margoles, H. R. [1 ]
Gomez-Lobo, V. [2 ]
Veis, J. H. [1 ]
Sherman, M. J. [1 ]
Moore, J., Jr. [3 ]
机构：
[1] Washington Hosp Ctr, Dept Nephrol, Washington, DC 20010 USA
[2] Georgetown Univ Hosp, Dept OB GYN, Washington, DC 20007 USA
[3] Georgetown Univ, Transplant Inst, Washington, DC USA
来源：
TRANSPLANTATION PROCEEDINGS | 2014年 / 46卷 / 01期
关键词：
SIROLIMUS; RECIPIENT; IMMUNOSUPPRESSION;
D O I：
10.1016/j.transproceed.2013.09.029
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Pregnancy after kidney transplantation is becoming more common as more patients of childbearing age are undergoing successful transplantation. There is limited evidence on the safety and efficacy of mammalian target of rapamycin inhibitors during pregnancy, which are considered Category C. We will review the use of this class of medications in pregnancy, which is currently contraindicated due to risk of fetal complications. We will also present the case of a successful pregnancy and renal outcome in a 33-year-old kidney transplant recipient who was administered everolimus throughout pregnancy.
引用
收藏
页码：281 / 283
页数：3
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