Rapid Decay of Anti-SARS-CoV-2 Antibodies in Persons with Mild Covid-19

被引:820
|
作者
Ibarrondo, F. Javier [1 ]
Fulcher, Jennifer A. [1 ]
Yang, Otto O. [1 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA
来源
NEW ENGLAND JOURNAL OF MEDICINE | 2020年 / 383卷 / 11期
基金
美国国家卫生研究院;
关键词
CORONAVIRUS;
D O I
10.1056/NEJMc2025179
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Among 34 volunteers who had recovered from mild Covid-19 illness, antiviral antibodies to the receptor-binding domain of the viral spike protein declined with a mean half-life of approximately 36 days after recovery. Whether these results predict the duration of viral immunity in persons recovering from more severe cases of Covid-19 or those exposed to vaccines is unknown.
引用
收藏
页码:1085 / 1087
页数:3
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