PHENIX reports on electromagnetic and hadronic observables in large data sets of p+p, d+Au and Au+Au collisions at various cms energies. Initial state effects in cold nuclear matter are quantified by centrality dependent pi(0), eta, reconstructed jets and psi' measurements. Using the first run of the new EBIS ion source at RHIC, we report first results for particle flow (nu(1)and V-2) and quarkonium production in U+U and Cu+Au collisions. Hot matter created in Au+Au is characterized using event-plane dependent HBT and dielectrons. Parton-medium interactions are investigated using high P-T single hadrons, gamma-hadron correlations and heavy flavor decay electrons identified with the newly installed VTX detector.