New C2-symmetric six-membered carbene ligands for asymmetric diethylzinc addition of arylaldehydes

被引：8

作者：

Zhou, Bihui ^{[1
,2
]}

Li, Zijing ^{[1
]}

Yang, Chen ^{[1
]}

Li, Linlin ^{[1
]}

Fan, Limei ^{[1
]}

Huang, Hongxia ^{[1
]}

Li, Jie ^{[1
]}

机构：

[1] Zhejiang Univ City Coll, Sch Med, Dept Pharm, 48 Huzhou Rd, Hangzhou 310015, Zhejiang, Peoples R China

[2] Zhejiang Univ, Coll Pharmaceut Siences, Hangzhou 310058, Zhejiang, Peoples R China

来源：

ARKIVOC | 2018年

基金：

中国国家自然科学基金;

关键词：

N-Heterocyclic carbene; tetrahydropyrimidinium; amino alcohols; asymmetric diethylzinc addition; chiral secondary alcohols; STEREODIRECTING LIGANDS; HETEROCYCLIC CARBENES; METAL-COMPLEXES; NHC LIGANDS; SALTS; REAGENTS;

D O I：

10.24820/ark.5550190.p010.410

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of new six-membered NHC precursors were prepared by simply esterification of their parent compounds. Their applicability in asymmetric diethylzinc addition of arylaldehydes has been demonstrated and the corresponding secondary alcohol was obtained with good yields and moderate enantioselectivities. [GRAPHICS] .

引用

页码：1 / 10

页数：10

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