A review of recent developments and applications of morphometry/stereology in lung research

被引：32

作者：

Muehlfeld, Christian ^{[1
,2
,3
]}

Hegermann, Jan ^{[1
,3
]}

Wrede, Christoph ^{[1
,3
]}

Ochs, Matthias ^{[1
,2
,3
]}

机构：

[1] Hannover Med Sch, Inst Funct & Appl Anat, D-30625 Hannover, Germany

[2] Biomed Res Endstage & Obstruct Lung Dis Hannover, Hannover, Germany

[3] Cluster Excellence REBIRTH Regenerat Biol Reconst, Hannover, Germany

来源：

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY | 2015年 / 309卷 / 06期

关键词：

design-based stereology; fibrosis; serial block face scanning electron microscopy; morphometry; emphysema; HYPOXIC PULMONARY-HYPERTENSION; HYPEROXIA-INDUCED LUNG; EXPERIMENTAL BRONCHOPULMONARY DYSPLASIA; MIGRATION INHIBITORY FACTOR; INDUCED AIRWAY FIBROSIS; GLYCATION END-PRODUCTS; MESENCHYMAL STEM-CELLS; ELECTRON-MICROSCOPY; NEONATAL-RATS; MOUSE MODEL;

D O I：

10.1152/ajplung.00047.2015

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Design-based stereology is the gold standard of morphometry in lung research. Here, we analyze the current use of morphometric and stereological methods in lung research and provide an overview on recent methodological developments and biological observations made by the use of stereology. Based on this analysis we hope to provide useful recommendations for a good stereological practice to further the use of advanced and unbiased stereological methods.

引用

页码：L526 / L536

页数：11

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