Developmental expression of the mouse MHC Q genes

被引:10
|
作者
Wang, Q
Flaherty, L
机构
[1] NEW YORK STATE DEPT HLTH,WADSWORTH CTR LABS & RES,ALBANY,NY 12201
[2] SUNY ALBANY,SCH PUBL HLTH,DEPT BIOMED SCI,ALBANY,NY 12201
来源
EUROPEAN JOURNAL OF IMMUNOGENETICS | 1996年 / 23卷 / 02期
关键词
D O I
10.1111/j.1744-313X.1996.tb00273.x
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
To investigate the role of class Ib genes in the Q region of the mouse major histocompatibility complex (MHC), the developmental expression and foetal tissue distribution of the e genes were studied in the C57BL/6 mouse. Using RNase protection assays, we examined Q gene expression in a wide spectrum of foetal tissues at different stages of gestation. Q4, Q6 and Q8 were widely expressed in a variety of tissues. In contrast, the expression of Q1 was restricted to the thymus and intestinal epithelium.
引用
收藏
页码:121 / 127
页数:7
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