An open-label pilot study of vemurafenib in previously treated metastatic melanoma patients with brain metastases.

被引:16
|
作者
Dummer, R.
Rinderknecht, J.
Goldinger, S. M.
Wagner, I.
Mitchell, L.
Veronese, M. L.
Nick, S.
Hilfiker, P.
Gobbi, S.
机构
[1] Univ Zurich Hosp, CH-8091 Zurich, Switzerland
[2] F Hoffmann La Roche, Basel, Switzerland
[3] F Hoffmann La Roche, Reinach, Switzerland
[4] MRI Bethanien, Zurich, Switzerland
关键词
D O I
10.1200/jco.2011.29.15_suppl.8548
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
8548
引用
收藏
页数:1
相关论文
共 50 条
  • [1] OPEN-LABEL PILOT STUDY OF VEMURAFENIB IN PREVIOUSLY TREATED METASTATIC MELANOMA (MM) PATIENTS (PTS) WITH SYMPTOMATIC BRAIN METASTASES (BM)
    Dummer, R.
    Goldinger, S.
    Turtschi, C.
    Eggmann, N.
    Michielin, O.
    Mitchell, L.
    Veronese, L.
    Hilfiker, P. R.
    Rinderknecht, J. D.
    ANNALS OF ONCOLOGY, 2012, 23 : 366 - 366
  • [2] Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study
    McArthur, G. A.
    Maio, M.
    Arance, A.
    Nathan, P.
    Blank, C.
    Avril, M. -F.
    Garbe, C.
    Hauschild, A.
    Schadendorf, D.
    Hamid, O.
    Fluck, M.
    Thebeau, M.
    Schachter, J.
    Kefford, R.
    Chamberlain, M.
    Makrutzki, M.
    Robson, S.
    Gonzalez, R.
    Margolin, K.
    ANNALS OF ONCOLOGY, 2017, 28 (03) : 634 - 641
  • [3] AN OPEN-LABEL, MULTICENTRE SAFETY STUDY OF VEMURAFENIB IN PATIENTS WITH METASTATIC MELANOMA
    Blank, C.
    Del Vecchio, M.
    Ascierto, P. A.
    Queirolo, P.
    Hauschild, A.
    Arance, A.
    Brown, M.
    Mitchell, L.
    Veronese, L.
    Larkin, J.
    ANNALS OF ONCOLOGY, 2012, 23 : 366 - 366
  • [4] Vemurafenib in patients with BRAFV600 mutation-positive melanoma with symptomatic brain metastases: Final results of an open-label pilot study
    Dummer, Reinhard
    Goldinger, Simone M.
    Turtschi, Christian P.
    Eggmann, Nina B.
    Michielin, Olivier
    Mitchell, Lada
    Veronese, Luisa
    Hilfiker, Paul Rene
    Felderer, Lea
    Rinderknecht, Jeannine D.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 (03) : 611 - 621
  • [5] Vemurafenib in patients with BRAFV600 mutated metastatic melanoma: an open-label, multicentre, safety study
    Larkin, James
    Del Vecchio, Michele
    Ascierto, Paolo A.
    Krajsova, Ivana
    Schachter, Jacob
    Neyns, Bart
    Espinosa, Enrique
    Garbe, Claus
    Sileni, Vanna Chiarion
    Gogas, Helen
    Miller, Wilson H., Jr.
    Mandala, Mario
    Hospers, Geke A. P.
    Arance, Ana
    Queirolo, Paola
    Hauschild, Axel
    Brown, Michael P.
    Mitchell, Lada
    Veronese, Luisa
    Blank, Christian U.
    LANCET ONCOLOGY, 2014, 15 (04): : 436 - 444
  • [6] A single-arm, open-label, US expanded access study of vemurafenib in patients with metastatic melanoma.
    Schuchter, Lynn Mara
    Flaherty, Lawrence E.
    Hamid, Omid
    Linette, Gerald P.
    Hallmeyer, Sigrun
    Gonzalez, Rene
    Cowey, Charles Lance
    Pavlick, Anna C.
    Kudrik, Fred J.
    Lawson, David H.
    Margolin, Kim Allyson
    Ribas, Antoni
    McDermott, David F.
    Khatcheressian, James L.
    Flaherty, Keith T.
    Day, Bann-Mo
    Linke, Rolf Gerhard
    Hainsworth, John D.
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [7] A Single-Arm, Open-Label, Expanded Access Study of Vemurafenib in Patients With Metastatic Melanoma in the United States
    Flaherty, Lawrence
    Hamid, Omid
    Linette, Gerald
    Schuchter, Lynn
    Hallmeyer, Sigrun
    Gonzalez, Rene
    Cowey, C. Lance
    Pavlick, Anna
    Kudrik, Fred
    Curti, Brendan
    Lawson, David
    Chapman, Paul B.
    Margolin, Kim
    Ribas, Antoni
    McDermott, David
    Flaherty, Keith
    Cranmer, Lee
    Hodi, F. Stephen
    Day, Bann-Mo
    Linke, Rolf
    Hainsworth, John
    CANCER JOURNAL, 2014, 20 (01): : 18 - 24
  • [8] Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial
    Margolin, Kim
    Ernstoff, Marc S.
    Hamid, Omid
    Lawrence, Donald
    McDermott, David
    Puzanov, Igor
    Wolchok, Jedd D.
    Clark, Joseph I.
    Sznol, Mario
    Logan, Theodore F.
    Richards, Jon
    Michener, Tracy
    Balogh, Agnes
    Heller, Kevin N.
    Hodi, F. Stephen
    LANCET ONCOLOGY, 2012, 13 (05): : 459 - 465
  • [9] Open-label, multicenter safety study of vemurafenib in patients with BRAFV600 mutation-positive metastatic melanoma
    Larkin, James M. G.
    Del Vecchio, Michele
    Ascierto, Paolo Antonio
    Schachter, Jacob
    Garbe, Claus
    Neyns, Bart
    Mandala, Mario
    Lorigan, Paul
    Miller, Wilson H.
    Guminski, Alexander David
    Berking, Carola
    Rutkowski, Piotr
    Queirolo, Paola
    Hauschild, Axel
    Arance, Ana Maria
    Brown, Michael Paul
    Mitchell, Lada
    Veronese, Maria Luisa
    Blank, Christian U.
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [10] AN OPEN-LABEL MULTICENTER PHASE II TRIAL OF AVISCUMINE IN PREVIOUSLY TREATED PATIENTS WITH UNRESECTABLE STAGE IV METASTATIC MELANOMA
    Uwe, Trefzer
    Ralf, Gutzmer
    Tabea, Wilhelm
    Florian, Schenck
    Katharina, Kaehler C.
    Volkmar, Jacobi
    Klaus, Witthohn
    Hans, Lentzen
    Peter, Mohr
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S7 - S7