Survival after a diagnosis of testicular germ cell cancers in Germany and the United States, 2002-2006: A high resolution study by histology and age

被引：27

作者：

Stang, A. ^{[1
,2
]}

Jansen, L. ^{[3
]}

Trabert, B. ^{[4
]}

Rusner, C. ^{[1
]}

Eberle, A. ^{[5
]}

Katalinic, A. ^{[6
]}

Emrich, K. ^{[7
]}

Holleczek, B. ^{[8
]}

Brenner, H. ^{[3
]}

机构：

[1] Univ Halle Wittenberg, Inst Klin Epidemiol, Med Fak, D-06097 Halle, Germany

[2] Boston Univ, Sch Publ Hlth, Boston, MA USA

[3] German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany

[4] NCI, Div Canc Epidemiol & Genet, NIH, Rockville, MD 20852 USA

[5] Leibniz Inst Prevent Res & Epidemiol, Bremen, Germany

[6] Med Univ Lubeck, Inst Canc Epidemiol, Canc Registry Schleswig Holstein, Lubeck, Germany

[7] Canc Registry Rhineland Palatinate, Inst Med Biostat Epidemiol & Informat, Mainz, Germany

[8] Saarland Canc Registry, Saarbrucken, Germany

来源：

CANCER EPIDEMIOLOGY | 2013年 / 37卷 / 04期

关键词：

Testicular neoplasms; Germinoma; Seminoma; Nonseminomatous germ cell tumor; Survival; Germany; United States; PERIOD ANALYSIS; TRENDS; EUROPE; CLASSIFICATION; TUMORS; WALES; EUROCARE-4; CARCINOMA; MORTALITY; ENGLAND;

D O I：

10.1016/j.canep.2013.03.017

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Introduction: The aim of this study was to provide detailed age-specific (5-year age groups) and histology-specific (histologic subtypes of seminoma and nonseminoma) relative survival estimates of testicular germ cell cancer patients in Germany and the United States (U.S.) for the years 2002-2006 and to compare these estimates between countries. Methods: We pooled data from 11 cancer registries of Germany and used data from the U.S. (SEER-13 database) including 11,508 and 10,774 newly diagnosed cases (1997-2006) in Germany and the U.S., respectively. We estimated 5-year relative survival (5-year-RS) by histology and age based on period analysis. Results: 5-year-RS for testicular germ cell tumors was 96.7% and 96.3% in Germany and the U.S., respectively. 5-Year-RS for spermatocytic seminoma was close to 100% in both countries. 5-Year-RS for nonseminoma was lower than for classical seminoma in Germany (93.3% versus 97.6%) and the U.S. (91.0% versus 98.2%). Among nonseminomas, choriocarcinomas provided the lowest 5-year-RS in both countries (Germany 80.1%, U.S. 79.6%). Age-specific 5-year-RS for seminoma showed only little variation by age. 5-Year-RS for nonseminomas tended to be lower at higher ages, especially for malignant teratoma. Discussion: This is the first study that provides up-to-date survival estimates for testicular cancer by histology and age in Germany and the U.S. Survival after a diagnosis of testicular cancer is very comparable between Germany and the U.S. 5-Year-RS for spermatocytic seminoma was close to 100% and the lowest 5-year-RS occurred among choriocarcinoma. Higher age at diagnosis is associated with a poorer prognosis among nonseminoma patients. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：492 / 497

页数：6