Antibacterial activity of selected metabolites from Chilean lichen species against methicillin-resistant staphylococci

被引：16

作者：

Celenza, Giuseppe ^{[1
]}

Segatore, Bernardetta ^{[1
]}

Setacci, Domenico ^{[1
]}

Perilli, Mariagrazia ^{[1
]}

Brisdelli, Fabrizia ^{[1
]}

Bellio, Pierangelo ^{[1
]}

Piovano, Marisa ^{[2
]}

Garbarino, Juan A. ^{[2
]}

Amicosante, Gianfranco ^{[1
]}

Nicoletti, Marcello ^{[3
]}

机构：

[1] Univ Aquila, Dept Biomed Sci & Technol, I-67100 Laquila, Italy

[2] Univ Tecn Federico Santa Maria, Dept Chem, Valparaiso, Chile

[3] Univ Sapienza, Dept Environm Biol, Rome, Italy

来源：

NATURAL PRODUCT RESEARCH | 2013年 / 27卷 / 17期

关键词：

lichen secondary metabolites; methicillin-resistant staphylococci; antimicrobial resistance; antibacterial activity; ANTIMICROBIAL ACTIVITY; USNIC ACID; AUREUS; CONSTITUENTS; COMBINATION; VANCOMYCIN; ATRANORIN; EXTRACTS;

D O I：

10.1080/14786419.2012.730043

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The invitro antibacterial activities of eight compounds isolated from lichens, collected in several Southern regions of Chile (including Antarctica), were evaluated against methicillin-resistant clinical isolates strains of Staphylococcus aureus, Staphylococcus haemolyticus and Staphylococcus warneri. The minimum inhibitory concentrations, calculated in microdilution, were ranging from 8 mu gmL(-1) for sphaerophorin to 1024 mu gmL(-1) for fumarprotocetraric acid. These findings suggest, however, that the natural compounds from lichens are good candidates for the individuation of novel templates for the development of new antimicrobial agents or combinations of drugs for chemotherapy.

引用

页码：1528 / 1531

页数：4

共 50 条

[1] IN VITRO ACTIVITY OF TIGECYCLINE AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCI
Tunckanat, Ferda
Saribas, Zeynep
Ercis, Serpil
MIKROBIYOLOJI BULTENI, 2009, 43 (02): : 211 - 215
[2] IN-VITRO ACTIVITY OF SPARFLOXACIN AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCI
WALLRAUCH, C
VOSS, A
MILATOVIC, D
BRAVENY, I
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1995, 45-1 (06): : 723 - 725
[3] INVITRO ACTIVITY OF CIPROFLOXACIN AGAINST METHICILLIN-SUSCEPTIBLE AND METHICILLIN-RESISTANT STAPHYLOCOCCI
GAHRNHANSEN, B
SOGAARD, P
ARPI, M
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1987, 6 (05) : 581 - 584
[4] COMPARATIVE ANTIBACTERIAL ACTIVITY OF L-695,256, A CARBAPENEM ACTIVE AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCI
RYLANDER, M
ROLLOF, J
JACOBSSON, K
NORRBY, SR
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (05) : 1178 - 1181
[5] ACTIVITY OF TETRACYCLINE, DOXYCYCLINE, AND MINOCYCLINE AGAINST METHICILLIN-SUSCEPTIBLE AND METHICILLIN-RESISTANT STAPHYLOCOCCI
MINUTH, JN
HOLMES, TM
MUSHER, DM
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1974, 6 (04) : 411 - 414
[6] In vitro activity of evernimicin and selected antibiotics against methicillin-resistant staphylococci: a 24-country study
Goering, R
Nord, CE
Hare, R
Sabatelli, F
CLINICAL MICROBIOLOGY AND INFECTION, 2000, 6 (10) : 549 - 556
[7] Antibacterial activity of hydroxychalcone against methicillin-resistant Staphylococcus aureus
Sato, M
Tsuchiya, H
Miyazaki, T
Fujiwara, S
Yamaguchi, R
Kureshiro, H
Iinuma, M
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 1996, 6 (04) : 227 - 231
[8] SYNERGY OF SULBACTAM AND AMPICILLIN AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCI
CHIN, NX
NEU, NM
NEU, HC
DRUGS UNDER EXPERIMENTAL AND CLINICAL RESEARCH, 1986, 12 (12) : 939 - 942
[9] INVITRO ACTIVITY OF CEPHALOSPORINS AGAINST METHICILLIN-RESISTANT, COAGULASE-NEGATIVE STAPHYLOCOCCI
LAVERDIERE, M
PETERSON, PK
VERHOEF, J
WILLIAMS, DN
SABATH, LD
JOURNAL OF INFECTIOUS DISEASES, 1978, 137 (03): : 245 - 250
[10] Methicillin-resistant staphylococci isolated from animals
van Duijkeren, E
Box, ATA
Heck, MEOC
Wannet, WJB
Fluit, AC
VETERINARY MICROBIOLOGY, 2004, 103 (1-2) : 91 - 97

← 1 2 3 4 5 →