LUSPATERCEPT (ACE-536) INCREASES HEMOGLOBIN AND DECREASES TRANSFUSION BURDEN AND LIVER IRON CONCENTRATION IN ADULTS WITH BETA-THALASSEMIA: PRELIMINARY RESULTS FROM A PHASE 2 STUDY

被引：0

作者：

Piga, A. ^{[1
]}

Perrotta, S. ^{[2
]}

Borgna-Pignatti, C. ^{[3
]}

Gamberini, M. R. ^{[3
]}

Melpignano, A. ^{[4
]}

Voskaridou, E. ^{[5
]}

Caruso, V. ^{[6
]}

Filosa, A. ^{[7
]}

Aydinok, Y. ^{[8
]}

Zhang, X. ^{[9
]}

Wilson, D. ^{[9
]}

Laadem, A. ^{[10
]}

Sherman, M. ^{[9
]}

Attie, K. ^{[9
]}

机构：

[1] Univ Turin, Turin, Italy

[2] Univ Naples 2, Naples, Italy

[3] Univ Ferrara, I-44100 Ferrara, Italy

[4] Osped A Perrino, Brindisi, Italy

[5] Laikon Gen Hosp, Athens, Greece

[6] Garibaldi Hosp, Catania, Italy

[7] AORN A Cardarelli, Naples, Italy

[8] Ege Univ, Pediat Hematol, Izmir, Turkey

[9] Acceleron Pharma, Cambridge, MA USA

[10] Celgene Corp, Summit, NJ USA

来源：

HAEMATOLOGICA | 2015年 / 100卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

S136

引用

页码：17 / 17

页数：1

共 29 条

[1] ACE-536 Increases Hemoglobin and Decreases Transfusion Burden and Serum Ferritin in Adults with Beta-Thalassemia: Preliminary Results from a Phase 2 Study
Piga, Antonio G.
Perrotta, Silverio
Melpignano, Angela
Borgna-Pignatti, Caterina
Voskaridou, Ersi
Caruso, Vincenzo
Filosa, Aldo
Aydinok, Yesim
Condon, Carrie
Wilson, Dawn M.
Laadem, Adberrahmane
Sherman, Matthew L.
Attie, Kenneth M.
BLOOD, 2014, 124 (21)
[2] ACE-536 INCREASES HEMOGLOBIN LEVELS IN ADULTS WITH BETA-THALASSEMIA: PRELIMINARY RESULTS FROM A PHASE 2 STUDY
Piga, A.
Melpignano, A.
Perrotta, S.
Borgna-Pignatti, C.
Caruso, V.
Voskaridou, E.
Filosa, A.
Aydinok, Y.
Condon, C.
Wilson, D.
Sherman, M.
Attie, K.
HAEMATOLOGICA, 2014, 99 : 230 - 231
[3] Luspatercept Increases Hemoglobin, Decreases Transfusion Burden and Improves Iron Overload in Adults with Beta-Thalassemia
Piga, Antonio G.
Tartaglione, Immacolata
Gamberini, Rita
Voskaridou, Ersi
Melpignano, Angela
Ricchi, Paolo
Caruso, Vincenzo
Pietrangelo, Antonello
Zhang, Xiaosha
Wilson, Dawn M.
Leneus, Ashley
Laadem, Abderrahmane
Sherman, Matthew L.
Attie, Kenneth M.
BLOOD, 2016, 128 (22)
[4] Luspatercept (ACE-536) Reduces Disease Burden, Including Anemia, Iron Overload, and Leg Ulcers, in Adults with Beta-Thalassemia: Results from a Phase 2 Study
Piga, Antonio
Perrotta, Silverio
Gamberini, M. Rita
Voskaridou, Ersi
Melpignano, Angela
Filosa, Aldo
Pietrangelo, Antonello
Caruso, Vincenzo
Forni, Gian Luca
Zhang, Xiaosha
Bellevue, Ashley
Wilson, Dawn
Laadem, Abderrahmane
Sherman, Matthew L.
Attie, Kenneth M.
BLOOD, 2015, 126 (23)
[5] LUSPATERCEPT DECREASES TRANSFUSION BURDEN AND LIVER IRON CONCENTRATION IN REGULARLY TRANSFUSED ADULTS WITH BETA-THALASSEMIA
Piga, A.
Perrotta, S.
Melpignano, A.
Borgna-Pignatti, C.
Gamberini, M. R.
Voskaridou, E.
Caruso, V.
Ricchi, P.
Pietrangelo, A.
Zhang, X.
Wilson, D.
Bellevue, A.
Laadem, A.
Sherman, M.
Attie, K.
HAEMATOLOGICA, 2016, 101 : 338 - 339
[6] LUSPATERCEPT INCREASES HEMOGLOBIN AND DECREASES TRANSFUSION BURDEN IN ADULTS WITH B-THALASSEMIA
Piga, A.
Tartaglione, I.
Gamberini, R.
Voskaridou, E.
Melpignano, A.
Ricchi, P.
Caruso, V.
Pietrangelo, A.
Zhang, X.
Wilson, D.
Leneus, A.
Laadem, A.
Sherman, M. L.
Attie, K. M.
Linde, P. G.
HAEMATOLOGICA, 2017, 102 : 15 - 16
[7] LUSPATERCEPT INCREASES HEMOGLOBIN, REDUCES LIVER IRON CONCENTRATION, AND IMPROVES QUALITY OF LIFE IN NON-TRANSFUSION DEPENDENT ADULTS WITH BETA-THALASSEMIA
Piga, A.
Perrotta, S.
Melpignano, A.
Borgna-Pignatti, C.
Gamberini, M. R.
Voskaridou, E.
Caruso, V.
Ricchi, P.
Pietrangelo, A.
Zhang, X.
Wilson, D.
Bellevue, A.
Laadem, A.
Sherman, M.
Attie, K.
HAEMATOLOGICA, 2016, 101 : 304 - 304
[8] ACE-536 Increases Hemoglobin and Reduces Transfusion Burden in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS): Preliminary Results from a Phase 2 Study
Platzbecker, Uwe
Germing, Ulrich
Giagounidis, Aristoteles
Goetze, Katharina
Kiewe, Philipp
Mayer, Karin
Ottman, Oliver
Radsak, Markus P.
Wolff, Thomas
Haase, Detlef
Hankin, Monty
Wilson, Dawn M.
Laadem, Adberrahmane
Sherman, Matthew L.
Attie, Kenneth M.
BLOOD, 2014, 124 (21)
[9] LUSPATERCEPT DECREASES TRANSFUSION BURDEN AND LIVER IRON CONCENTRATION IN REGULARLY TRANSFUSED ADULTS WITH β-THALASSAEMIA
Piga, Antonio G.
Perrotta, Silverio
Melpignano, Angela
Borgna-Pignatti, Caterina
Gamberini, M. Rita
Voskaridou, Ersi
Caruso, Vincenzo
Ricchi, Paolo
Pietrangelo, Antonello
Zhang, Xiaosha
Wilson, Dawn M.
Bellevue, Ashley
Laadem, Abderrahmane
Sherman, Matthew L.
Attie, Kenneth M.
HAEMATOLOGICA, 2017, 102 : 89 - 90
[10] ACE-536 INCREASES HEMOGLOBIN LEVELS IN PATIENTS WITH LOW OR INTERMEDIATE-1 RISK MYELODYSPLASTIC SYNDROMES (MDS): PRELIMINARY RESULTS FROM A PHASE 2 STUDY
Platzbecker, U.
Germing, U.
Giagounidis, A.
Goetze, K.
Kiewe, P.
Mayer, K.
Ottmann, O.
Radsak, M.
Wolff, T.
Hankin, M.
Wilson, D.
Sherman, M.
Attie, K.
HAEMATOLOGICA, 2014, 99 : 500 - 500

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