A Mutant Type 2 Herpes Simplex Virus Deleted for the Protein Kinase Domain of the ICP10 Gene Is a Potent Oncolytic Virus

被引：0
|
作者：
Fu, Xinping [1 ,2 ]
Tao, Lihua [1 ]
Zhang, Xiaoliu [1 ]
机构：
[1] Baylor Coll Med, Ctr Cell & Gene Therapy, Houston, TX 77030 USA
[2] Chongqing Med Univ, Affiliated Hosp 2, Chongqing, Peoples R China
来源：
MOLECULAR THERAPY | 2006年 / 13卷
关键词：
D O I：
10.1016/j.ymthe.2006.08.180
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
157
引用
收藏
页码：S61 / S62
页数：2
相关论文
共 50 条
  • [1] A mutant type 2 herpes simplex virus deleted for the protein kinase domain of the ICP10 gene is a potent oncolytic virus
    Fu, Xinping
    Tao, Lihua
    Cai, Rong
    Prigge, Jonathan
    Zhang, Xiaoliu
    MOLECULAR THERAPY, 2006, 13 (05) : 882 - 890
  • [2] Vaccine potential of a herpes simplex virus type 2 mutant deleted in the PK domain of the large subunit of ribonucleotide reductase (ICP10)
    Aurelian, L
    Kokuba, H
    Smith, CC
    VACCINE, 1999, 17 (15-16) : 1951 - 1963
  • [3] An HSV-2-based oncolytic virus deleted in the PK domain of the ICP10 gene is a potent inducer of apoptotic death in tumor cells
    Fu, X.
    Tao, L.
    Zhang, X.
    GENE THERAPY, 2007, 14 (16) : 1218 - 1225
  • [4] An HSV-2-based oncolytic virus deleted in the PK domain of the ICP10 gene is a potent inducer of apoptotic death in tumor cells
    X Fu
    L Tao
    X Zhang
    Gene Therapy, 2007, 14 : 1218 - 1225
  • [5] PROTEIN-KINASE ACTIVITY ASSOCIATED WITH THE LARGE SUBUNIT OF HERPES-SIMPLEX VIRUS TYPE-2 RIBONUCLEOTIDE REDUCTASE (ICP10)
    CHUNG, TD
    WYMER, JP
    SMITH, CC
    KULKA, M
    AURELIAN, L
    JOURNAL OF VIROLOGY, 1989, 63 (08) : 3389 - 3398
  • [6] Cell Type-Specific Induction and Inhibition of Apoptosis by Herpes Simplex Virus Type 2 ICP10
    Han, Jin-Young
    Miller, Sara A.
    Wolfe, Teresa M.
    Pourhassan, Hoda
    Jerome, Keith R.
    JOURNAL OF VIROLOGY, 2009, 83 (06) : 2765 - 2769
  • [7] The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for immediate-early gene expression and virus growth
    Smith, CC
    Peng, T
    Kulka, M
    Aurelian, L
    JOURNAL OF VIROLOGY, 1998, 72 (11) : 9131 - 9141
  • [8] MYRISTYLATION AND POLYLYSINE-MEDIATED ACTIVATION OF THE PROTEIN-KINASE DOMAIN OF THE LARGE SUBUNIT OF HERPES-SIMPLEX VIRUS TYPE-2 RIBONUCLEOTIDE REDUCTASE (ICP10)
    CHUNG, TD
    WYMER, JP
    KULKA, M
    SMITH, CC
    AURELIAN, L
    VIROLOGY, 1990, 179 (01) : 168 - 178
  • [9] ATP and SH3 binding sites in the protein kinase of the large subunit of herpes simplex virus type 2 of ribonucleotide reductase (ICP10)
    Nelson, JW
    Zhu, J
    Smith, CC
    Kulka, M
    Aurelian, L
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (29) : 17021 - 17027
  • [10] A TRUNCATED PROTEIN-KINASE DOMAIN OF THE LARGE SUBUNIT OF HERPES-SIMPLEX VIRUS TYPE-2 RIBONUCLEOTIDE REDUCTASE (ICP10) EXPRESSED IN ESCHERICHIA-COLI
    LUO, JH
    SMITH, CC
    KULKA, M
    AURELIAN, L
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1991, 266 (31) : 20976 - 20983
12345