Crystal Structure of a Cleaved, Stabilized HIV-1 Env Trimer in Complex with a Glycan-Dependent Broadly Neutralizing Antibody at 4.7 Å

被引：0
|
作者：
Julien, J. [1 ]
Cupo, A. [2 ]
Sok, D. [1 ]
Stanfield, R. L. [1 ]
Lyumkis, D. [1 ]
Deller, M. C. [1 ]
Burton, D. R. [1 ]
Sanders, R. W. [3 ]
Moore, J. P. [2 ]
Ward, A. B. [1 ]
Wilson, I. A. [1 ]
机构：
[1] Scripps Res Inst, La Jolla, CA 92037 USA
[2] Cornell Univ, Weill Med Coll, New York, NY 10021 USA
[3] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands
来源：
AIDS RESEARCH AND HUMAN RETROVIRUSES | 2013年 / 29卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：A165 / A166
页数：2
相关论文
共 50 条
  • [1] Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies
    Bonsignori, Mattia
    Kreider, Edward F.
    Fera, Daniela
    Meyerhoff, R. Ryan
    Bradley, Todd
    Wiehe, Kevin
    Alam, S. Munir
    Aussedat, Baptiste
    Walkowicz, William E.
    Hwang, Kwan-Ki
    Saunders, Kevin O.
    Zhang, Ruijun
    Gladden, Morgan A.
    Monroe, Anthony
    Kumar, Amit
    Xia, Shi-Mao
    Cooper, Melissa
    Louder, Mark K.
    McKee, Krisha
    Bailer, Robert T.
    Pier, Brendan W.
    Jette, Claudia A.
    Kelsoe, Garnett
    Williams, Wilton B.
    Morris, Lynn
    Kappes, John
    Wagh, Kshitij
    Kamanga, Gift
    Cohen, Myron S.
    Hraber, Peter T.
    Montefiori, David C.
    Trama, Ashley
    Liao, Hua-Xin
    Kepler, Thomas B.
    Moody, M. Anthony
    Gao, Feng
    Danishefsky, Samuel J.
    Mascola, John R.
    Shaw, George M.
    Hahn, Beatrice H.
    Harrison, Stephen C.
    Korber, Bette T.
    Haynes, Barton F.
    SCIENCE TRANSLATIONAL MEDICINE, 2017, 9 (381)
  • [2] Single Glycan Binding by a Broadly Neutralizing Antibody to HIV-1 Env
    Garces, F.
    Sok, D.
    Kim, H. J.
    McBride, R.
    Kong, L.
    Hua, Y.
    Paulson, J. C.
    Ward, A. B.
    Burton, D. R.
    Wilson, I. A.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2013, 29 (11) : A187 - A187
  • [3] Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape
    Moore, Penny L.
    Gray, Elin S.
    Wibmer, C. Kurt
    Bhiman, Jinal N.
    Nonyane, Molati
    Sheward, Daniel J.
    Hermanus, Tandile
    Bajimaya, Shringkhala
    Tumba, Nancy L.
    Abrahams, Melissa-Rose
    Lambson, Bronwen E.
    Ranchobe, Nthabeleng
    Ping, Lihua
    Ngandu, Nobubelo
    Karim, Quarraisha Abdool
    Karim, Salim S. Abdool
    Swanstrom, Ronald I.
    Seaman, Michael S.
    Williamson, Carolyn
    Morris, Lynn
    NATURE MEDICINE, 2012, 18 (11) : 1688 - +
  • [4] Broadly neutralizing antibodies that recognize the HIV-1 Env glycan shield
    Wilson, Ian A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [5] Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies
    Julien, J.
    Kong, L.
    Pejchal, R.
    Khayat, R.
    Lee, J.
    Stanfield, R. S.
    Walker, L. M.
    Doores, K. J.
    Folkowska, E.
    Poignard, P.
    Depetris, R.
    Sanders, R. W.
    Koff, W. C.
    Moore, J. P.
    Ward, A. B.
    Burton, D. R.
    Wilson, I. A.
    RETROVIROLOGY, 2012, 9
  • [6] Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies
    J Julien
    L Kong
    R Pejchal
    R Khayat
    J Lee
    RS Stanfield
    LM Walker
    KJ Doores
    E Folkowska
    P Poignard
    R Depetris
    RW Sanders
    WC Koff
    JP Moore
    AB Ward
    DR Burton
    IA Wilson
    Retrovirology, 9 (Suppl 2)
  • [7] Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer
    He, Linling
    Lin, Xiaohe
    de Val, Natalia
    Saye-Francisco, Karen L.
    Mann, Colin J.
    Augst, Ryan
    Morris, Charles D.
    Azadnia, Parisa
    Zhou, Bin
    Sok, Devin
    Ozorowski, Gabriel
    Ward, Andrew B.
    Burton, Dennis R.
    Zhu, Jiang
    FRONTIERS IN IMMUNOLOGY, 2017, 8
  • [8] Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers
    Falkowska, Emilia
    Le, Khoa M.
    Ramos, Alejandra
    Doores, Katie J.
    Lee, Jeong Hyun
    Blattner, Claudia
    Ramirez, Alejandro
    Derking, Ronald
    van Gils, Marit J.
    Liang, Chi-Hui
    Mcbride, Ryan
    von Bredow, Benjamin
    Shivatare, Sachin S.
    Wu, Chung-Yi
    Chan-Hui, Po-Ying
    Liu, Yan
    Feizi, Ten
    Zwick, Michael B.
    Koff, Wayne C.
    Seaman, Michael S.
    Swiderek, Kristine
    Moore, John P.
    Evans, David
    Paulson, James C.
    Wong, Chi-Huey
    Ward, Andrew B.
    Wilson, Ian A.
    Sanders, Rogier W.
    Poignard, Pascal
    Burton, Dennis R.
    IMMUNITY, 2014, 40 (05) : 657 - 668
  • [9] Antibody-antigen distance of broadly neutralizing HIV-1 antibodies correlates with glycan-shield coverage of HIV-1 envelope trimer
    Lee, M.
    Rawi, R.
    Shapiro, L.
    Kwong, P.
    Chuang, G. -Y.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2021, 24
  • [10] HIV-1 env trimer structure
    Bradbury, Jane
    LANCET INFECTIOUS DISEASES, 2013, 13 (12): : 1018 - 1018
12345