Efficient synthesis of N-alkylformimidoyl cyanides

被引：5
|
作者：
Perosa, A [1 ]
Selva, M [1 ]
Tundo, P [1 ]
机构：
[1] Univ Venice, Dipartimento Sci Ambientali, I-30123 Venice, Italy
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 42期
关键词：
D O I：
10.1016/S0040-4039(99)01608-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
N-Alkylformimidoyl cyanides (RRCHN=CHCN, 1) were obtained through a very efficient oxidation of N-alkylaminoacetonitriles (RRCHNHCH2CN, 2) by aq. NaOCl. The reaction was run under very mild and simple conditions and afforded products (as E/Z isomer mixtures; E/Z ratio of 70-99%) in short reaction times (30-180 min), and in good to excellent yields (67-97%). (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：7573 / 7576
页数：4
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