Toward live-cell imaging of dopamine neurotransmission with fluorescent neurotransmitter analogues

被引：3

作者：

Lin, Hui-Jen ^{[1
,2
]}

Lu, Hsueh-Han ^{[1
,2
]}

Liu, Kuan-Miao ^{[3
]}

Chau, Chi-Min ^{[3
]}

Hsieh, You-Zung ^{[1
,2
]}

Li, Yaw-Kuen ^{[1
,2
]}

Liau, Ian ^{[1
,2
]}

机构：

[1] Natl Chiao Tung Univ, Dept Appl Chem, Hsinchu 30010, Taiwan

[2] Natl Chiao Tung Univ, Inst Mol Sci, Hsinchu 30010, Taiwan

[3] Chung Shan Med Univ, Sch Med Appl Chem, Taichung 40201, Taiwan

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 74期

关键词：

SK-N-SH; SEROTONIN TRANSPORTER; PC12; CELLS; IN-VIVO; BRAIN; EXPRESSION; RELEASE; INHIBITORS;

D O I：

10.1039/c5cc03050a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a novel 'fluorescent dopamine' that possesses essential features of natural dopamine. Our method is simple and is readily extended to monoamine neurotransmitters such as L-norepinephrine, serotonin and GABA, providing a more practical approach. Because of its compatibility with sensitive fluorescent measurements, we envisage that our approach will have a broad range of applications in neural research.

引用

页码：14080 / 14083

页数：4

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