Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease

被引：112

作者：

Romito, LMA

Scerrati, M

Contarino, MF

Bentivoglio, AR

Tonali, P

Albanese, A

机构：

[1] Ist Nazl Neurol Carlo Besta, I-20133 Milan, Italy

[2] Univ Cattolica Sacro Cuore, Ist Neurochirurg, Rome, Italy

[3] Univ Cattolica Sacro Cuore, Ist Neurol, Rome, Italy

来源：

NEUROLOGY | 2002年 / 58卷 / 10期

关键词：

D O I：

10.1212/WNL.58.10.1546

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Twenty-two patients with PD received bilateral implants for high frequency stimulation of the subthalamic nucleus. The patients were treated for more than 1 year (up to 36 months). At the last visit, the Unified Parkinson Disease Rating Scale (UPDRS) motor score without medication improved by 50.2% (p < 0.001) and the UPDRS activities of daily living score improved by 68.4% (p < 0.001). The most common long-lasting adverse events were hypophonia and dysarthria; transient events were increased sexuality and mania. The surgical procedure induced transient intraoperative psychosis in seven patients.

引用

页码：1546 / 1550

页数：5

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