Phosphoinositides in membrane traffic

被引:183
作者
Corvera, S [1 ]
D'Arrigo, A
Stenmark, H
机构
[1] Univ Massachusetts, Sch Med, Program Mol Med, Worcester, MA 01605 USA
[2] Univ Massachusetts, Sch Med, Dept Cell Biol, Worcester, MA 01605 USA
[3] Norwegian Radium Hosp, Dept Biochem, Inst Canc Res, N-0310 Oslo, Norway
关键词
D O I
10.1016/S0955-0674(99)80066-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Phosphoinositides serve as direct local modulators or recruiters of the protein machineries that control membrane trafficking. In the past year, examples of phosphoinositide effecters include regulators of small GTPases in coat assembly, dynamin in clathrin coated vesicle formation and FYVE finger proteins in endocytic membrane traffic. A novel phosphoinositide appears to regulate effecters involved in the formation of multivesicular endosomes.
引用
收藏
页码:460 / 465
页数:6
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