Highly sensitive and selective rhodamine Schiff base "off-on" chemosensors for Cu2+ imaging in living cells

被引:92
|
作者
Yang, Zheng [1 ]
She, Mengyao [1 ]
Zhang, Jin [1 ]
Chen, Xiaoxiang [1 ]
Huang, Yangyang [1 ]
Zhu, Hengyan [1 ]
Liu, Ping [1 ]
Li, Jianli [1 ]
Shi, Zhen [1 ]
机构
[1] NW Univ Xian, Coll Chem & Mat Sci, Minist Educ Key Lab Synthet & Nat Funct Mol Chem, Xian 710069, Shaanxi, Peoples R China
关键词
Rhodamine; Fluorescent chemosensor; Cu2+ ion; Cinnamaldehyde; Cell imaging; FLUORESCENT SENSOR; AQUEOUS-MEDIA; COPPER-ION; PROBE; NANOPARTICLES; MECHANISMS; BINDING; STRESS; CU(II); OXYGEN;
D O I
10.1016/j.snb.2012.07.035
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Three new rhodamine Schiff base sensors 1a-1c have been designed and synthesized as highly sensitive and selective "off-on" chemosensors for Cu2+ detection via the rhodamine ring-opening approach. The sensors display remarkably Cu2+-selective orange fluorescence and pink color switch over a wide range of tested metal ions. Fluorescent imaging of Cu2+ in living cells is also successfully demonstrated. (C) 2012 Published by Elsevier B.V.
引用
收藏
页码:482 / 487
页数:6
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