Multicultural society is a reality of a society that cannot be rebutted in the era of globalization. It is composed of various models of communities. Every community model has its own character and history. Indonesia is a multicultural country spreading from Sabang to Merauke, from Mianggas to Rote Island. For Indonesian, a good understanding of the multicultural community concept is a basic necessity to get better knowledge as a basic foundation for the government to manage a good multicultural society in the globalization era. Thus, this study tries to make the religion of Islam as a framework of scientific thinking in explaining the multicultural society. It tries to get the paradigm of secular thinking. It understands that religion only limits on faith to the strength the supernatural which is realized in the form of worship. Through the methodology of history and the approach of mentality study assisted, it is found that the religion of Islam is potential to be a framework of scientific thinking that can be used in explaining the phenomenon of multicultural society. This study also finds that Islam is not only able to explain the reality of multicultural society, but it is also able to give the solution to a better condition for the modern men in managing multicultural society. As a result, they are happy, prosperous, humane, enjoying life, and living in peace on the complexity of life problems in the globalization era.
