Functional linguistic specificity of the left frontal aslant tract for spontaneous speech fluency: Evidence from intraoperative language mapping

被引：23

作者：

Dragoy, Olga ^{[1
]}

Zyryanov, Andrey ^{[1
]}

Bronov, Oleg ^{[2
]}

Gordeyeva, Elizaveta ^{[1
]}

Gronskaya, Natalya ^{[3
]}

Kryuchkova, Oksana ^{[4
]}

Klyuev, Evgenij ^{[5
]}

Kopachev, Dmitry ^{[6
]}

Medyanik, Igor ^{[7
]}

Mishnyakova, Lidiya ^{[8
]}

Pedyash, Nikita ^{[9
]}

Pronin, Igor ^{[10
]}

Reutov, Andrey ^{[11
]}

Sitnikov, Andrey ^{[8
]}

Stupina, Ekaterina ^{[1
]}

Yashin, Konstantin ^{[7
]}

Zhirnova, Valeriya ^{[1
]}

Zuev, Andrey ^{[9
]}

机构：

[1] Natl Res Univ Higher Sch Econ, Ctr Language & Brain, 21-4 Staraya Basmannaya St,Off 510, Moscow 105066, Russia

[2] Natl Med & Surg Ctr, Dept Radiol, Moscow, Russia

[3] Natl Res Univ Higher Sch Econ, Fac Humanities, Nizhnii Novgorod, Russia

[4] Cent Clin Hosp, Dept Radiol, Outpatient Hlth Ctr Business Adm President Russia, Moscow, Russia

[5] Privolzhsky Res Med Univ, Dept Radiol, Nizhnii Novgorod, Russia

[6] Natl Med Res Ctr Neurosurg, Dept Neurosurg, Moscow, Russia

[7] Privolzhsky Res Med Univ, Dept Neurosurg, Nizhnii Novgorod, Russia

[8] Minist Healthcare Russian Federat, Dept Neurosurg, Fed Ctr Treatment & Rehabil, Moscow, Russia

[9] Natl Med & Surg Ctr, Dept Neurosurg, Moscow, Russia

[10] Natl Med Res Ctr Neurosurg, Dept Neuroradiol, Moscow, Russia

[11] Cent Clin Hosp, Dept Neurosurg, Outpatient Hlth Ctr Business Adm President Russia, Moscow, Russia

来源：

BRAIN AND LANGUAGE | 2020年 / 208卷

基金：

俄罗斯基础研究基金会;

关键词：

Frontal aslant tract; Spontaneous speech fluency; Tractography; Direct electrical stimulation; SUPPLEMENTARY MOTOR AREA; WHITE-MATTER TRACTS; ELECTRICAL-STIMULATION; BROCAS AREA; STRUCTURAL CONNECTIVITY; CORTICAL STIMULATION; DYNAMIC APHASIA; VERBAL FLUENCY; AWAKE SURGERY; BRAIN;

D O I：

10.1016/j.bandl.2020.104836

中图分类号：

R36 [病理学]; R76 [耳鼻咽喉科学];

学科分类号：

100104 ; 100213 ;

摘要：

The left frontal aslant tract (FAT) has been proposed to be relevant for language, and specifically for spontaneous speech fluency. However, there is missing causal evidence that stimulation of the FAT affects spontaneous speech, and not language production in general. We present a series of 12 neurosurgical cases with awake language mapping of the cortex near the left FAT. Tasks for language mapping included the commonly used action picture naming, and sentence completion, tapping more specifically into spontaneous speech. A task dissociation was found in 10 participants: while being stimulated on specific sites, they were able to name a picture but could not complete a sentence. Overlaying of these sites on preoperative white-matter tract reconstructions revealed that in each individual case they were located on cortical terminations of the FAT. This corroborates the language functional specificity of the left FAT as a tract underlying fluent spontaneous speech.

引用

页数：14

共 3 条

[1] Left frontal aslant tract and lexical selection: Evidence from frontal lobe lesions
Zyryanov, Andrey
Malyutina, Svetlana
Dragoy, Olga
NEUROPSYCHOLOGIA, 2020, 147
[2] Alzheimer's Disease Detection from Spontaneous Speech through Combining Linguistic Complexity and (Dis)Fluency Features with Pretrained Language Models
Qiao, Yu
Yin, Xuefeng
Wiechmann, Daniel
Kerz, Elma
INTERSPEECH 2021, 2021, : 3805 - 3809
[3] Limited Plastic Potential of the Left Ventral Premotor Cortex in Speech Articulation: Evidence From Intraoperative Awake Mapping in Glioma Patients
van Geemen, Kim
Herbet, Guillaume
Moritz-Gasser, Sylvie
Duffau, Hugues
HUMAN BRAIN MAPPING, 2014, 35 (04) : 1587 - 1596

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