The autoimmunologist: geoepidemiology, a new center of gravity, and prime time for autoimmunity

被引:119
|
作者
Shoenfeld, Yehuda [1 ,2 ]
Selmi, Carlo [3 ,4 ]
Zimlichman, Eyal [5 ,6 ,7 ]
Gershwin, M. Eric [4 ]
机构
[1] Tel Aviv Univ, Sackler Fac Med, Sheba Med Ctr, Ctr Autoimmune Dis,Dept Med B, IL-69978 Tel Aviv, Israel
[2] Tel Aviv Univ, Sackler Fac Med, Incumbent Laura Schwarz Kipp Chair Res Autoimmune, IL-69978 Tel Aviv, Israel
[3] Univ Milan, Ist Clin Humanitas, IRCCS, Dept Internal Med, Milan, Italy
[4] Univ Calif Davis, Div Rheumatol Allergy & Clin Immunol, Davis, CA USA
[5] Chaim Sheba Med Ctr, Dept Med B, IL-52621 Tel Hashomer, Israel
[6] Chaim Sheba Med Ctr, Clin Performance Assessment Unit, IL-52621 Tel Hashomer, Israel
[7] Chaim Sheba Med Ctr, Talpiot Med Leadership Program, IL-52621 Tel Hashomer, Israel
关键词
Autoimmunology; Center of Excellence; Biologics; Female predominance;
D O I
10.1016/j.jaut.2008.08.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
There are currently over 100 human diseases that are considered to be autoimmune or chronic inflammatory affecting 5-10% of the world population and spanning through all medical specialties. As a result, health care costs are enormous and the clinical management is often challenging particularly, considering the comorbidity rates and the multi-organ involvement of each condition. We herein propose the creation of a new specialist, coined the autoimmunologist, to overcome the current limitations in the diagnostic process and clinical follow-up of patients with autoimmune diseases. More importantly, we also propose the creation of regional centers of excellence in autoimmunity where clinical research and management, as well as basic research may be united and interact in ideal synergy to ultimately create real translational research and provide better health care. (C) 2008 Elsevier Ltd. All rights reserved.
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页码:325 / 330
页数:6
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