A mechanistic model for the aging of human skin

被引：30
|
作者：
Giacomoni, PU
Rein, G
机构：
[1] Clin Labs Inc, Melville, NY 11747 USA
[2] Estee Lauder Res Pk, Melville, NY 11747 USA
来源：
MICRON | 2004年 / 35卷 / 03期
关键词：
human skin; skin aging; inflammation; microinflammatory model of skin aging; neuropeptides; age spots; dry skin; wrinkles;
D O I：
10.1016/j.micron.2003.11.004
中图分类号：
TH742 [显微镜];
学科分类号：
摘要：
The microinflammatory model of skin aging is described. This model accounts for the loss of elasticity, resiliene and flexibility of the dermis, as well as for the appearance of wrinkles and for the thinning of the epidermis which are associated with aging. The lack of appropriate apparatuses for the correct measurements of skin hydration does not allow one to test this model for its predictive capability of the appearance of dry skin with age. The micro-inflammatory model of skin aging fails to predict the appearance of age spots on the surface of the skin. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：179 / 184
页数：6
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