MECHANISM OF ACTION AND THERAPEUTIC APPLICATION OF AURORA KINASE B INHIBITION IN c-MYC OVEREXPRESSING MEDULLOBLASTOMA

被引：0
|
作者：
Diaz, Roberto [1 ]
Golbourn, Brian [1 ]
Faria, Claudia [1 ]
Shih, David [1 ]
MacKenzie, Danielle [1 ]
Picard, Daniel [1 ]
Bryant, Melissa [1 ]
Smith, Christian [1 ]
Taylor, Michael [1 ]
Huang, Annie [1 ]
Rutka, James [1 ]
机构：
[1] Hosp Sick Children, Toronto, ON M5G 1X8, Canada
来源：
NEURO-ONCOLOGY | 2013年 / 15卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
0076
引用
收藏
页码：20 / 20
页数：1
相关论文
共 50 条
  • [1] Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma
    Diaz, Roberto Jose
    Golbourn, Brian
    Faria, Claudia
    Picard, Daniel
    Shih, David
    Raynaud, Denis
    Leadly, Michael
    MacKenzie, Danielle
    Bryant, Melissa
    Bebenek, Matthew
    Smith, Christian A.
    Taylor, Michael D.
    Huang, Annie
    Rutka, James T.
    ONCOTARGET, 2015, 6 (05) : 3359 - 3374
  • [2] SUBGROUP TARGETED THERAPY FOR C-MYC-OVEREXPRESSING MEDULLOBLASTOMA WITH AURORA KINASE B/C INHIBITOR AZD1152-HQPA
    Diaz, Roberto J.
    Golbourn, Brian
    Picard, Daniel
    Smith, Christian
    Huang, Annie
    Rutka, James
    NEURO-ONCOLOGY, 2012, 14 : 33 - 33
  • [3] Therapeutic potential of the cyclin-dependent kinase inhibitor on c-Myc overexpressing esophageal adenocarcinoma
    Hassan, Sazzad
    Awasthi, Niranjan
    Schwarz, Margaret A.
    Schwarz, Roderich E.
    Holzen, Urs V.
    CANCER RESEARCH, 2016, 76
  • [4] Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer
    Hassan, Md Sazzad
    Cwidak, Nicholas
    Johnson, Chloe
    Daester, Silvio
    Eppenberger-Castori, Serenella
    Awasthi, Niranjan
    Li, Jun
    Schwarz, Margaret A.
    von Holzen, Urs
    FRONTIERS IN PHARMACOLOGY, 2021, 12
  • [5] Aurora B facilitates cholangiocarcinoma progression by stabilizing c-Myc
    Liu, Ke
    Zhou, Xuxuan
    Huang, Fei
    Liu, Lihao
    Xu, Zijian
    Gao, Chongqing
    Zhang, Keke
    Hong, Jian
    Yao, Nan
    Cheng, Guohua
    ANIMAL MODELS AND EXPERIMENTAL MEDICINE, 2024, 7 (05) : 626 - 640
  • [6] Aurora B facilitates cholangiocarcinoma progression by stabilizing c-Myc
    Ke Liu
    Xuxuan Zhou
    Fei Huang
    Lihao Liu
    Zijian Xu
    Chongqing Gao
    Keke Zhang
    Jian Hong
    Nan Yao
    Guohua Cheng
    Animal Models and Experimental Medicine, 2024, 7 (05) : 626 - 640
  • [7] Pan cancer therapeutic inhibition of oncogenic c-MYC by the engineered destabilized 3'UTR of c-MYC
    Awah, Chidiebere U.
    CANCER RESEARCH, 2024, 84 (06)
  • [8] Aurora kinase A mediates c-Myc's oncogenic effects in hepatocellular carcinoma
    Lu, Longfeng
    Han, Han
    Tian, Yuan
    Li, Wenjuan
    Zhang, Jinxiang
    Feng, Maohui
    Li, Youjun
    MOLECULAR CARCINOGENESIS, 2015, 54 (11) : 1467 - 1479
  • [9] Pim kinase-dependent inhibition of c-Myc degradation
    Zhang, Y.
    Wang, Z.
    Li, X.
    Magnuson, N. S.
    ONCOGENE, 2008, 27 (35) : 4809 - 4819
  • [10] Pim kinase-dependent inhibition of c-Myc degradation
    Y Zhang
    Z Wang
    X Li
    N S Magnuson
    Oncogene, 2008, 27 : 4809 - 4819
12345