Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize and kill tumor associated antigen STEAP1+tumour cells in vivo

被引:0
|
作者
Schirmer, D. [1 ]
Grunewald, T. [2 ]
Klar, R. [3 ]
Schmidt, O. [1 ]
Wohlleber, D. [4 ]
Rubio, R. Alba [2 ]
Uckert, W. [5 ]
Thiel, U. [1 ]
Protzer, U. [6 ]
Busch, D. [7 ]
Krackhardt, A. [3 ]
Burdach, S. [1 ]
Richter, G. [1 ]
机构
[1] Tech Univ Munich, Klinikum Rechts Isar, Childrens Canc Res Ctr, Munich, Germany
[2] Ludwig Maximilians Univ Munchen, Inst Pathol, Munich, Germany
[3] Tech Univ Munich, Klinikum Rechts Isar, Dept Med 3, Hematol & Oncol, Munich, Germany
[4] Tech Univ Munich, Klinikum Rechts Isar, Inst Mol Immunol Expt Oncol, Munich, Germany
[5] Humboldt Univ, Max Delbruck Ctr Mol Med, Berlin, Germany
[6] Tech Univ Munich, Inst Virol, Munich, Germany
[7] Tech Univ Munich, Klinikum Rechts Isar, Inst Med Microbiol Immunol & Hyg, Munich, Germany
关键词
D O I
10.1016/S0959-8049(16)32874-X
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
280
引用
收藏
页码:S93 / S93
页数:1
相关论文
共 50 条
  • [1] Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity
    Schirmer, David
    Gruenewald, Thomas G. P.
    Klar, Richard
    Schmidt, Oxana
    Wohlleber, Dirk
    Rubio, Rebeca Alba
    Uckert, Wolfgang
    Thiel, Uwe
    Bohne, Felix
    Busch, Dirk H.
    Krackhardt, Angela M.
    Burdach, Stefan
    Richter, Guenther H. S.
    ONCOIMMUNOLOGY, 2016, 5 (06):
  • [2] Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAPI with high specificity
    Schirmer, David
    Klar, Richard
    Schmidt, Oxana
    Wohlleber, Dirk
    Uckert, Wolfgang
    Thiel, Uwe
    Bohne, Felix
    Busch, Dirk H.
    Krackhardt, Angela M.
    Burdach, Stefan
    Richter, Gunther H.
    CANCER RESEARCH, 2016, 76
  • [3] Transgenic antigen-specific, allogeneic HLA-A*0201-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity
    Schirmer, D.
    Busch, D. H.
    Uckert, W.
    Krackhardt, A.
    Klar, R.
    Burdach, S.
    Richter, G.
    ONCOLOGY RESEARCH AND TREATMENT, 2016, 39 : 125 - 125
  • [4] TRANSGENIC ANTIGEN-SPECIFIC, ALLOGENEIC HLA-A*0201-RESTRICTED CYTOTOXIC T CELLS RECOGNIAE TUMOUR-ASSOCIATED TARGET ANTIGEN STEAP1 WITH HIGH SPECIFICITY
    David, Schirmer
    Dirk, Busch H.
    Wolfgang, Uckert
    Angela, Krackhardt
    Richard, Klar
    Stefan, Burdach
    Guenther, Richter H. S.
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S10 - S10
  • [5] Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells
    U Thiel
    S Pirson
    C Müller-Spahn
    H Conrad
    D H Busch
    H Bernhard
    S Burdach
    G H S Richter
    British Journal of Cancer, 2011, 104 : 948 - 956
  • [6] Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells
    Thiel, U.
    Pirson, S.
    Mueller-Spahn, C.
    Conrad, H.
    Busch, D. H.
    Bernhard, H.
    Burdach, S.
    Richter, G. H. S.
    BRITISH JOURNAL OF CANCER, 2011, 104 (06) : 948 - 956
  • [7] Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T-cells
    Thiel, U.
    Pirson, S.
    Mueller-Spahn, C.
    Conrad, H.
    Busch, D.
    Bernhard, H.
    Burdach, S.
    Richter, G.
    BONE MARROW TRANSPLANTATION, 2011, 46 : S56 - S56
  • [8] Erratum: Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells
    U Thiel
    S Pirson
    C Müller-Spahn
    H Conrad
    D H Busch
    H Bernhard
    S Burdach
    G H S Richter
    British Journal of Cancer, 2011, 105 : 596 - 596
  • [9] Generation and in vivo function of antigen-specific cytotoxic T cells by HLA-Ig coated artificial Antigen Presenting Cells
    Oelke, M
    Krueger, C
    Bennett, JD
    June, C
    Mackensen, A
    Schneck, JP
    FASEB JOURNAL, 2004, 18 (04): : A64 - A64
  • [10] Dendritic Cells Engineered to Express Defined Allo-HLA Peptide Complexes Induce Antigen-specific Cytotoxic T Cells Efficiently Killing Tumour Cells
    Stronen, E.
    Abrahamsen, I. W.
    Gaudernack, G.
    WAlchli, S.
    Munthe, E.
    Buus, S.
    Johansen, F. -E.
    Lund-Johansen, F.
    Olweus, J.
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2009, 69 (04) : 319 - 328