Collective Cell Migration: Wisdom of the Crowds Transforms a Negative Cue into a Positive One

被引:1
|
作者
Mayor, Roberto [1 ]
机构
[1] UCL, Dept Cell & Dev Biol, Gower St, London WC1E 6BT, England
关键词
SEMAPHORINS; GUIDANCE; MOTION;
D O I
10.1016/j.cub.2019.02.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Semaphorin ligands and their Plexin receptors are known to induce cell-cell repulsion. A new study now finds that protrusion collapse, induced by Semaphorin-5C-Plexin-A interactions at the cell-cell contact, promotes planar polarization and collective migration of follicular cells in Drosophila.
引用
收藏
页码:R205 / R207
页数:4
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