Extended ethidium bromide analogue as a triple helix intercalator: synthesis, photophysical properties and nucleic acids binding

被引：34
|
作者：
Tam, Victor K. [1 ]
Liu, Qi [1 ]
Tor, Yitzhak [1 ]
机构：
[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
来源：
CHEMICAL COMMUNICATIONS | 2006年 / 25期
关键词：
D O I：
10.1039/b604281c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Ethidium bromide has been extended by fusing an additional aromatic ring resulting in a larger intercalator with increased affinity for poly r(A) . r(U), poly d(A). d(T) and triple helices when compared to the parent heterocycle.
引用
收藏
页码：2684 / 2686
页数：3
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