Squamous Cell Carcinoma of the Tonsil Causing Small Bowel Perforation in the Setting of Metastasis and Treatment With Programmed Death-1 Inhibitors: A Case Report

被引：2

作者：

Dabek, Robert J. ^{[1
]}

Bizanti, Anas ^{[2
]}

Thomas, Samantha ^{[1
]}

Kalla, Abhishek ^{[3
]}

Hamdallah, Isam ^{[1
]}

机构：

[1] St Agnes Hosp, Dept Surg, Baltimore, MD 21229 USA

[2] St Agnes Hosp, Dept Internal Med, Baltimore, MD USA

[3] St Agnes Hosp, Dept Hematol & Oncol, Baltimore, MD USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2020年 / 12卷 / 09期

关键词：

head and neck neoplasms; gastrointestinal perforation; pd-1; inhibitors; visceral metastasis; SECONDARY;

D O I：

10.7759/cureus.10739

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Metastasis of extra-intestinal carcinoma to the gastrointestinal tract (GIT) is a rare event, most commonly occurring with malignant melanoma. Anti-PD-1 (programmed death-1) immunotherapeutic agents are immune checkpoint inhibitors with proven benefit across multiple cancer types, including squamous cell carcinoma of the head and neck (SCCHN). Here we describe a case of small bowel perforation attributed to a primary SCCHN metastasizing to the GIT in the setting of treatment with PD-1 inhibitors.

引用

页数：5

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