Oral Immunization of Mice with Lily Pollen Expressing HBsAg

被引：1
|
作者：
Park, Hee-Sung [1 ]
Park, Eun-Hye [1 ]
Heo, Young-Joo [1 ]
Heo, Yong [2 ]
机构：
[1] Catholic Univ Daegu, Dept Biotechnol, Gyongsan 712702, South Korea
[2] 'atholic Univ Daegu, Dept Occupat Hlth, Gyongsan 712702, South Korea
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2013年 / 77卷 / 12期
关键词：
Edible vaccine; HBsAg; lily pollen; transient expression; B SURFACE-ANTIGEN; IMMUNOGENICITY; VACCINE;
D O I：
10.1271/bbb.130531
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Lily pollen was developed to express HBsAg by Agrobacterium-mediated transformation. A double prime-boost strategy combining parenteral and oral HBsAg boosters was found to increase antibody titer levels 10-fold, as compared to a single process of priming and boosting. Lily pollen may prove a tool for oral vaccine development.
引用
收藏
页码：2492 / 2494
页数：3
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