Pyrrolothieno[1,4]diazepines .3. Synthesis of amino, hydrazino and mercapto derivatives

被引：7
|
作者：
Boulouard, M
Rault, S
Dallemagne, P
Alsaidi, A
Robba, M
机构：
[1] Ctr. d'Etud. Rech. Medicament N., U.F.R. des Sciences Pharmaceutiques, 14032 Caen
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 1996年 / 33卷 / 01期
关键词：
D O I：
10.1002/jhet.5570330115
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Treatment of 2-(2-formyl-1H-pyrrol-1-yl)-3-thiophenecarbonitrile by sodium percarbonate afforded, in a one-pot sequence and on a multigram scale, 5,6-dihydro-6-hydroxy-4H-pyrrolo[1,2-a]thieno-[3,2-f][1,4]diazepin-4-one whose reactivity towards various nucleophiles like amines, hydrazines and thiols was evaluated.
引用
收藏
页码：87 / 91
页数：5
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