Three anti-tumor saponins from Albizia julibrissin

被引：68
|
作者：
Zheng, L
Zheng, J
Zhao, YY
Wang, B
Wu, LJ
Liang, H [1 ]
机构：
[1] Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
[2] Shanyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2006年 / 16卷 / 10期
基金：
中国国家自然科学基金;
关键词：
Albizia julibrissin; julibroside J(29); julibroside J(30); juliborside J(31); anti-tumor activity;
D O I：
10.1016/j.bmcl.2006.02.009
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Three new triterpenoid saponins, julibroside J(29) (1), julibroside J(30) (2), and julibroside J(31) (3), were isolated from the stem bark of Albizia julibrissin Durazz. (Leguminosae) by using chromatographic method. Their structures were established by spectroscopic methods. Compounds 1, 2, and 3 displayed significant anti-tumor activities in vitro against PC-3M-1E8, HeLa, and MDA-MB-435 cancer cell lines at 10 mu M assayed by SRB and MTT methods. (C) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2765 / 2768
页数：4
相关论文
共 50 条
  • [1] Three new triterpenoid saponins from Albizia julibrissin
    Wang, Xu-Da
    Han, Qing-Hua
    Zhang, Jun
    Zhang, Qing-Ping
    Tu, Peng-Fei
    Liang, Hong
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 21 (06) : 535 - 541
  • [2] Diastereoisomeric saponins from Albizia julibrissin
    Zou, K
    Tong, WY
    Liang, H
    Cui, JR
    Tu, GZ
    Zhao, YY
    Zhang, RY
    CARBOHYDRATE RESEARCH, 2005, 340 (07) : 1329 - 1334
  • [3] Cytotoxic oleanane triterpenoid saponins from Albizia julibrissin
    Han, Qinghua
    Qian, Yi
    Wang, Xuda
    Zhang, Qingying
    Cui, Jingrong
    Tu, Pengfei
    Liang, Hong
    FITOTERAPIA, 2017, 121 : 183 - 193
  • [4] Three new oleanane triterpenoid saponins acetylated with monoterpenoid acid from Albizia julibrissin
    Zheng, Lu
    Zheng, Jian
    Zhang, Qingying
    Wang, Bin
    Zhao, Yuying
    Wu, Lijun
    FITOTERAPIA, 2010, 81 (07) : 859 - 863
  • [5] Structural identification of two diastereoisomeric saponins from Albizia julibrissin
    Zou, K
    Zhao, YY
    Wang, B
    Li, DY
    Cai, SQ
    Zhang, RY
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 1999, 20 (12): : 1877 - 1882
  • [6] Structural Identification of Two Diastereoisomeric Saponins from Albizia Julibrissin
    Zou, Kun
    Zhao, Yu-Ying
    Wang, Bin
    Li, De-Yu
    Cai, Shao-Qing
    Zhang, Ru-Yi
    Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities, 1999, 20 (12): : 1881 - 1882
  • [7] Two diastereomeric saponins with cytotoxic activity from Albizia julibrissin
    Zou, K
    Zhao, YY
    Tu, GZ
    Cui, JR
    Jia, ZH
    Zhang, RY
    CARBOHYDRATE RESEARCH, 2000, 324 (03) : 182 - 188
  • [8] Cytotoxic Triterpenoid Saponins Acetylated with Monoterpenoid Acid from Albizia julibrissin
    Zou, Kun
    Zhang, Qing-Ying
    Wang, Bin
    Cui, Jing-Rong
    Zhao, Yu-Ying
    Zhang, Ru-Yi
    HELVETICA CHIMICA ACTA, 2010, 93 (10) : 2100 - 2106
  • [9] Synthesis of a tetra- and a trisaccharide related to an anti-tumor saponin "Julibroside J28" from Albizia julibrissin
    Roy, Bimalendu
    Pramanik, Kausikisankar
    Mukhopadhyay, Balaram
    GLYCOCONJUGATE JOURNAL, 2008, 25 (02) : 157 - 166
  • [10] Synthesis of a tetra- and a trisaccharide related to an anti-tumor saponin “Julibroside J28” from Albizia julibrissin
    Bimalendu Roy
    Kausikisankar Pramanik
    Balaram Mukhopadhyay
    Glycoconjugate Journal, 2008, 25
12345