Modern global transformations have determined the need to search for conditions and sources that ensure competitive, sustainable and safe economic development. Tax regulation is one of the guarantees of sustainable regional development. Tax regulation is an element of the system of public administration aimed at developing socio-economic indicators of the economy and is exercised directly through the mechanism of tax functions' implementation. In this regard, if we talk about the implementation of the fiscal function, tax regulation is carried out here with a view to generate financial resources for the further solution of socio-economic and other problems. If we consider the mechanism for implementing other functions of taxes, then in this case tax regulation is carried out to prevent the decline and stimulate the growth of production and reproduction processes, to ensure scientific and technological progress and to raise the volume of investment, income and savings of the population, etc. In order to assess the results of tax regulation it is necessary to determine them, i.e. to evaluate the performance of the given parameters of the budget system revenues' execution; to determine the degree of influence of regulatory instruments of taxation on the budget system revenues and users of tax benefits. As the research has shown, tax regulation is a systematic mechanism of socio-economic development management and a well-established tool to achieve stated socio-economic objectives.