Synthesis of 3 or 3,3′-substituted BINOL ligands and their application in the asymmetric addition of diethylzinc to aromatic aldehydes

被引：29
|
作者：
Guo, QS [1 ]
Liu, B [1 ]
Lu, YN [1 ]
Jiang, FY [1 ]
Song, HB [1 ]
Li, JS [1 ]
机构：
[1] Nankai Univ, State Key Lab ElementoOrgan Chem, Tianjin 300071, Peoples R China
来源：
TETRAHEDRON-ASYMMETRY | 2005年 / 16卷 / 22期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/j.tetasy.2005.09.018
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Three new substituted BINOL ligands (R)-3-[4,6-bis(dimethylamino)-1,3,5-triazin-2-yl]-1,1'-bi-2-naphthol (R)-1, (R)3,3'-bis[4,6-bis(dimethylamino)-1,3,5 -triazin-2-yl]-1, 1'-bi-2-naphthol (R)-2 and 2,4-bis(2,2'-dihydroxy-1,1'-binaphthalen-3-yl)-6-(ptolyl)-1,3,5-triazine (R,R)-3 have been obtained by directed ortho-lithiation or Suzuki cross-coupling process. Ligand (R)-1 shows improved catalytic properties for the asymmetric diethylzinc addition to aromatic aldehydes. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3667 / 3671
页数：5
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