Carbon nanotube-liposome supramolecular nanotrains for intelligent molecular-transport systems

被引:67
|
作者
Miyako, Eijiro [1 ]
Kono, Kenji [2 ]
Yuba, Eiji [2 ]
Hosokawa, Chie [1 ]
Nagai, Hidenori [1 ]
Hagihara, Yoshihisa [1 ]
机构
[1] Natl Inst Adv Ind Sci & Technol, HRI, Ikeda, Osaka 5630026, Japan
[2] Osaka Prefecture Univ, Dept Appl Chem, Naka Ku, Sakai, Osaka 5998531, Japan
关键词
COMPOSITE; DELIVERY; MOTION;
D O I
10.1038/ncomms2233
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, several key technologies have not been sufficiently realized to achieve optimum performance of transportation methods. Here we show that a new type of supramolecular system comprising of carbon nanotubes and liposomes enables the directional transport and controlled release of carrier molecules, and allows an enzymatic reaction at a desired area. The study highlights important progress that has been made towards the development of biomimetic molecular-transport systems and various lab-on-a-chip applications, such as medical diagnosis, sensors, bionic computers and artificial biological networks.
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页数:9
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