The association studies of ADIPOQ with type 2 diabetes mellitus in Chinese populations

被引：15
|
作者：
Li, Yiping [1 ]
Yang, Ying [1 ]
Shi, Li [2 ,3 ]
Li, Xianli [1 ]
Zhang, Ying [1 ]
Yao, Yufeng [2 ,3 ]
机构：
[1] Second Peoples Hosp Yunnan Prov, Dept Endocrinol & Metab, Kunming 650021, Yunnan, Peoples R China
[2] Chinese Acad Med Sci, Inst Med Biol, Kunming 650118, Yunnan, Peoples R China
[3] Peking Union Med Coll, Kunming 650118, Yunnan, Peoples R China
来源：
DIABETES-METABOLISM RESEARCH AND REVIEWS | 2012年 / 28卷 / 07期
关键词：
ADIPOQ; diabetes mellitus; type; 2; single nucleotide polymorphisms; Chinese populations; SINGLE-NUCLEOTIDE POLYMORPHISMS; PLASMA ADIPONECTIN LEVELS; COMPLEMENT-RELATED PROTEIN; GENE-ENCODING ADIPONECTIN; FATTY-ACID OXIDATION; INSULIN-RESISTANCE; APM1; GENE; INFLAMMATORY MARKERS; SUSCEPTIBILITY GENES; PROMOTER VARIANTS;
D O I：
10.1002/dmrr.2309
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Adiponectin, which is secreted by the white adipose tissue, plays an important role in type 2 diabetes mellitus (T2DM) and its complications. Since 2002, many investigators explored the association between ADIPOQ single nucleotide polymorphisms and T2DM in different ethnic populations from different regions. In China, the results of numerous studies of the association between ADIPOQ and T2DM were not consistent, which may be caused by population-specific effects or environmental effects. This review describes the association between ADIPOQ and T2DM, the metabolic characteristics and the complications of T2DM in Chinese populations. Copyright (C) 2012 John Wiley & Sons, Ltd.
引用
收藏
页码：551 / 559
页数：9
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