Loss of ubiquitin-specific peptidase 18 (USP18) destabilizes the regulator of thermogenesis uncoupling protein-1 (UCP-1) and represses lung cancer growth

被引：0
|
作者：
Liu, Xi [1 ]
Lu, Yun [2 ]
Hu, Weiguo [1 ]
Chen, Zibo [1 ]
Mustachio, Lisa M. [1 ]
Roszik, Jason [1 ]
Zheng, Lin [1 ]
Kawakami, Masanori [1 ]
Chen, Yulong [1 ]
Freemantle, Sarah J. [3 ]
Dmitrovsky, Ethan [1 ]
机构：
[1] UT MD Anderson Canc Ctr, Houston, TX USA
[2] Geisel Sch Med Dartmouth, Hanover, NH USA
[3] Univ Illinois, Urbana, IL USA
来源：
CANCER RESEARCH | 2018年 / 78卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2018-2399
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2399
引用
收藏
页数：2
相关论文
共 7 条
  • [1] Loss of ubiquitin-specific peptidase 18 (USP18) causes cold sensitive mice by destabilizing the critical regulator of thermogenesis: uncoupling protein-1 (UCP-1)
    Liu, Xi
    Lu, Yun
    Zheng, Lin
    Sekula, David J.
    Freemantle, Sarah J.
    Dmitrovsky, Ethan
    CANCER RESEARCH, 2016, 76
  • [2] Loss of the ubiquitin-specific peptidase 18 (USP18) reduces lung cancer metastasis
    Chen, Zibo
    Zheng, Lin
    Chen, Yulong
    Kawakami, Masanori
    Mustachio, Lisa
    Roszik, Jason
    Liu, Xin
    Kurie, Jonathan
    Liu, Xi
    Dmitrovsky, Ethan
    CANCER RESEARCH, 2019, 79 (13)
  • [3] Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis
    Chen, Zibo
    Zheng, Lin
    Chen, Yulong
    Liu, Xiuxia
    Kawakami, Masanori
    Mustachio, Lisa Maria
    Roszik, Jason
    Ferry-Galow, Katherine V.
    Parchment, Ralph E.
    Liu, Xin
    Andresson, Thorkell
    Duncan, Gerard
    Kurie, Jonathan M.
    Rodriguez-Canales, Jaime
    Liu, Xi
    Dmitrovsky, Ethan
    CANCER BIOLOGY & THERAPY, 2022, 23 (01) : 265 - 280
  • [4] The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth
    Liu, Xi
    Lu, Yun
    Chen, Zibo
    Liu, Xiuxia
    Hu, Weiguo
    Zheng, Lin
    Chen, Yulong
    Kurie, Jonathan M.
    Shi, Mi
    Mustachio, Lisa Maria
    Adresson, Thorkell
    Fox, Stephen
    Roszik, Jason
    Kawakami, Masanori
    Freemantle, Sarah J.
    Dmitrovsky, Ethan
    MOLECULAR CANCER RESEARCH, 2021, 19 (04) : 667 - 677
  • [5] Loss of the ubiquitin protease USP18 represses KRAS mutant lung cancer tumorigenicity in mice by destabilizing KRAS protein
    Mustachio, Lisa Maria
    Lu, Yun
    Tafe, Laura J.
    Andrew, Angeline S.
    Memoli, Vincent
    Rodriguez-Canales, Jaime
    Villalobos, Pamela A.
    Wistuba, Ignacio
    Yu, Jun
    Lee, Jack J.
    Chinyengetere, Fadzai
    Sekula, David J.
    Liu, Xi
    Freemantle, Sarah J.
    Dmitrovsky, Ethan
    CANCER RESEARCH, 2016, 76
  • [6] Ubiquitin-specific peptidase 18 negatively regulates and inhibits lipopolysaccharide-induced sepsis by targeting transforming growth factor-β-activated kinase 1 activity
    Hu, Bin
    Ge, Chunhua
    Zhu, Chunqing
    INTERNATIONAL IMMUNOLOGY, 2021, 33 (09) : 461 - 468
  • [7] Loss of Ras GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) inhibits the progression of ovarian cancer in coordination with ubiquitin-specific protease 10 (USP10)
    Li, Mengyuan
    Tang, Yan
    Zuo, Xinzhao
    Meng, Silin
    Yi, Ping
    BIOENGINEERED, 2022, 13 (01) : 721 - 734
1