With the rapid growth of educational scale and student recruiment in recent years, the teaching quality is becoming a more serious problem. So it's urgent to establish a teaching quality guarantee system in college and univeristy. When designing the teaching quality guarantee system, a few principles must be take into consideration, such as the head of the faculty be the first responsibility person, all the staff be involved in the practice, the activity should be systematic and practical as well as extended. Teaching quality guarantee system is composed of teaching management, teaching research, teaching service, teaching assessment and teaching feedback. Among them, teaching management is the core, teaching service the basis, teaching assessment the fundament, teaching feedback the key and teaching research the necessary booster. They co-exist and interact with each other. They won't work when one is absent, let alone the effect of a system. Since 1990s, our country has witnessed a continuous development in colleges and universities. Consider the scale of running a school and the number of students at colleges and universities: the number amounted to 1867 by the end of 2006, (of which there were 720 undergraduate colleges, 1147 higher vocational colleges, and 318 independent colleges); the number of students was 25000000 and the gross enrollment rate of higher education was the 22%. Judging by the international standard, China has entered the phase of popularization of higher education. While at the same time, China is a country running a big education with limited finance. Confronted with the limited resources, we are in a dilemma to balance the quantity and quality: on the one hand, we should meet citizens' strong desire of receiving higher education through the increase of enrollment rate to the greatest extent; on the other hand, we also hope the increasing enrollment will not disturb the quality of higher education. However, the fact was that there appeared problem in the quality of teaching which cannot be ignored. It is acknowledged that teaching is the central work in colleges and universities and teaching quality is the lifeline to colleges. Therefore, establishing and improving the guarantee system of teaching quality of colleges and universities in China has become a pressing matter.