Management of Overt Hepatic Encephalopathy

被引：22

作者：

Khungar, Vandana ^{[1
,2
]}

Poordad, Fred ^{[1
,3
]}

机构：

[1] Cedars Sinai Med Ctr, Dept Med, Los Angeles, CA 90048 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Los Angeles, CA 90095 USA

[3] Cedars Sinai Med Ctr, Dept Surg, Los Angeles, CA 90048 USA

来源：

CLINICS IN LIVER DISEASE | 2012年 / 16卷 / 01期

关键词：

Hepatic encephalopathy; Liver disease; Cirrhosis; Overt hepatic encephalopathy; INTRAHEPATIC PORTOSYSTEMIC SHUNT; ORNITHINE-L-ASPARTATE; PORTAL-SYSTEMIC ENCEPHALOPATHY; RANDOMIZED CONTROLLED-TRIAL; ORAL ZINC SUPPLEMENTATION; DOUBLE-BLIND; RIFAXIMIN TREATMENT; LIVER-CIRRHOSIS; CLINICAL-TRIAL; AMMONIA LEVELS;

D O I：

10.1016/j.cld.2011.12.007

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatic encephalopathy (HE) is a potentially reversible state of impaired cognitive function or altered consciousness in patients with liver disease or portosystemic shunting. Overt HE is a particularly pressing problem. Given the many targets of treatment and lack of a clear singular cause of overt HE, there is no consensus on a single best treatment. Over the past several years, high-quality studies have been conducted on the various pharmacologic therapies for HE and, as more data emerge, hopefully HE will become a much more easily treated complication of decompensated liver disease.

引用

页码：73 / +

页数：18

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