Oxidative alkylation of alkenes with carbonyl compounds through concomitant 1,2-aryl migration by photoredox catalysis

被引：11
|
作者：
Lin, Zhaowei [1 ]
Lu, Maojian [1 ]
Liu, Boyi [1 ]
Gao, Jing [1 ]
Huang, Mingqiang [1 ]
Gan, Zhenhong [1 ]
Cai, Shunyou [1 ,2 ]
机构：
[1] Minnan Normal Univ, Sch Chem Chem Engn & Environm, Key Lab Modern Analyt Sci & Separat Technol Fujia, Zhangzhou 363000, Peoples R China
[2] Peking Univ, Sch Chem Biol & Biotechnol, Shenzhen Grad Sch, Key Lab Chem Genom Guangdong Prov, Shenzhen 518055, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2020年 / 44卷 / 37期
基金：
中国国家自然科学基金;
关键词：
ALPHA; ALPHA-DIARYL ALLYLIC ALCOHOLS; NITROGEN-CENTERED RADICALS; H BOND FUNCTIONALIZATION; EFFICIENT SYNTHESIS; ATOM-TRANSFER; LIGHT; GENERATION; REAGENTS; ARYL; DIFUNCTIONALIZATION;
D O I：
10.1039/d0nj03733h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Visible-light-enabled oxidative radical 1,2-alkylarylation of alpha-aryl allylic alcohols with carbonyl compounds has been established under mild conditions. An efficient and convenient protocol for the construction of a variety of 1,5-dicarbonyl compounds was realized in the presence of organic fluorophore 4CzIPN, hypervalent iodine(iii) reagent, and visible light irradiation. An obvious kinetic isotope effect was noticed, which helped in gaining insight into the mechanistic course.
引用
收藏
页码：16031 / 16035
页数：5
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