Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever

被引：60

作者：

Alpay, Nilufer ^{[1
]}

Sumnu, Abdullah ^{[1
]}

Caliskan, Yasar ^{[2
]}

Yazici, Halil ^{[2
]}

Turkmen, Aydin ^{[2
]}

Gul, Ahmet ^{[3
]}

机构：

[1] Istanbul Univ, Istanbul Sch Med, Dept Internal Med, Istanbul, Turkey

[2] Istanbul Univ, Istanbul Sch Med, Div Nephrol, Istanbul, Turkey

[3] Istanbul Univ, Istanbul Sch Med, Div Rheumatol, Istanbul, Turkey

来源：

RHEUMATOLOGY INTERNATIONAL | 2012年 / 32卷 / 10期

关键词：

Familial Mediterranean fever; Anakinra; Renal transplantation; Amyloidosis;

D O I：

10.1007/s00296-010-1474-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by self-limited recurrent attacks of fever and serositis. The serious complication of FMF is AA-type amyloidosis, which can result in end-stage renal disease. Although colchicine is effective in the majority of patients, there is no established treatment for those who are resistant or intolerant to colchicine. We herein report the efficacy of anakinra in a 52-year-old Turkish patient with FMF, secondary amyloidosis and renal transplant, who was resistant to colchicine treatment.

引用

页码：3277 / 3279

页数：3

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