Clinico-pathological correlation of UBE2C alterations in colorectal carcinoma and efficacy of UBE2C inhibition by proteosome inhibitor as a viable therapeutic target

被引:0
|
作者
Bu, Rong [1 ]
Bavi, Prashant [1 ]
Hussain, Azhar R. [1 ]
Jehan, Zeenath [1 ]
Abubaker, Jehad [1 ]
Al-Sanea, Nasser A. [1 ]
Abduljabbar, Alaa S. [1 ]
Ashari, Luai H. [1 ]
Al-Homoud, Samar J. [1 ]
Al-Dayel, Fouad [1 ]
George, Thara [1 ]
Qadri, Zeeshan [1 ]
Hassan, Nurul [1 ]
Prabhakaran, Sarita E. [1 ]
Ahmed, Magbool [1 ]
Uddin, Shahab [1 ]
Al-Kuraya, Khawla S. [1 ]
机构
[1] King Faisal Specialist Hosp & Res Ctr, Riyadh 11211, Saudi Arabia
关键词
D O I
10.1158/1538-7445.AM2011-2980
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2980
引用
收藏
页数:1
相关论文
共 50 条
  • [1] UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease
    Paisana, Eunice
    Cascao, Rita
    Custodia, Carlos
    Qin, Nan
    Picard, Daniel
    Pauck, David
    Carvalho, Tania
    Ruivo, Pedro
    Barreto, Clara
    Doutel, Delfim
    Cabecadas, Jose
    Roque, Rafael
    Pimentel, Jose
    Miguens, Jose
    Remke, Marc
    Barata, Joao T.
    Faria, Claudia C.
    NEURO-ONCOLOGY ADVANCES, 2023, 5 (01)
  • [2] System analysis identifies UBE2C as a novel oncogene target for adrenocortical carcinoma
    Huang, Renlun
    Guo, Lang
    Chen, Chiwei
    Xiang, Yuyang
    Li, Guohao
    Zheng, Jieyan
    Wu, Yanping
    Yuan, Xiu
    Zhou, Jianfu
    Gao, Wenxi
    Xiang, Songtao
    PLOS ONE, 2023, 18 (08):
  • [3] UBE2C promotes malignancy of cutaneous squamous cell carcinoma
    Luo, Ruiting
    Bai, Ruimin
    Guo, Jiaqi
    Xian, Ningyi
    Zheng, Yan
    SKIN RESEARCH AND TECHNOLOGY, 2023, 29 (11)
  • [4] A Comprehensive Bioinformatics Analysis of UBE2C in Cancers
    Dastsooz, Hassan
    Cereda, Matteo
    Donna, Daniela
    Oliviero, Salvatore
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (09)
  • [5] Expression and Clinical Significance of UBE2C in Neuroblastoma
    Yuan, X. J.
    Ma, X.
    Wang, L. F.
    PEDIATRIC BLOOD & CANCER, 2016, 63 : S207 - S208
  • [6] Contributions of UBE2C and UBE2S to meiotic progression of porcine oocytes
    Fujioka, Yoshie A.
    Onuma, Asuka
    Fujii, Wataru
    Sugiura, Koji
    Naito, Kunihiko
    JOURNAL OF REPRODUCTION AND DEVELOPMENT, 2018, 64 (03): : 253 - 259
  • [7] Bortezomib Stabilizes Mitotic Cyclins and Prevents Cell Cycle Progression via Inhibition of UBE2C in Colorectal Carcinoma
    Bavi, Prashant
    Uddin, Shahab
    Ahmed, Maqbool
    Jehan, Zeenath
    Bu, Rong
    Abubaker, Jehad
    Sultana, Mehar
    Al-Sanea, Nasser
    Abduljabbar, Alaa
    Ashari, Luai H.
    Alhomoud, Samar
    Al-Dayel, Fouad
    Prabhakaran, Sarita
    Hussain, Azhar R.
    Al-Kuraya, Khawla S.
    AMERICAN JOURNAL OF PATHOLOGY, 2011, 178 (05): : 2109 - 2120
  • [8] UBE2C promotes the progression of head and neck squamous cell carcinoma
    Jin, Zhenning
    Zhao, Xinyuan
    Cui, Li
    Xu, Xiangdong
    Zhao, Yutian
    Younai, Fariba
    Messadi, Diana
    Hu, Shen
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 523 (02) : 389 - 397
  • [9] The clinical significance of UBE2C gene in progression of renal cell carcinoma
    Chen, Zhiping
    Wang, Lanfeng
    EUROPEAN JOURNAL OF HISTOCHEMISTRY, 2021, 65 (02):
  • [10] UBE2C promotes rectal carcinoma via miR-381
    Zhang, Yan
    Tian, Suli
    Li, Xiaodong
    Ji, Yanchao
    Wang, Zhongcheng
    Liu, Chang
    CANCER BIOLOGY & THERAPY, 2018, 19 (03) : 230 - 238