Immunoprophylaxis against and prevention of recurrent viral hepatitis after liver transplantation

被引:25
|
作者
Laryea, Marie A. [2 ]
Watt, Kymberly D. [1 ]
机构
[1] Mayo Clin & Mayo Fdn, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
[2] Dalhousie Univ, Multiorgan Transplant Program, Halifax, NS, Canada
关键词
B IMMUNE GLOBULIN; HBV-RELATED CIRRHOSIS; TERM-FOLLOW-UP; VIRUS RECURRENCE; ADEFOVIR DIPIVOXIL; SURFACE-ANTIGEN; POSITIVE GRAFTS; LOW-RISK; LAMIVUDINE; PROPHYLAXIS;
D O I
10.1002/lt.23408
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The reinfection of the hepatic allograft with hepatitis B virus and hepatitis C virus can have important sequelae that result in poor long-term patient and graft survival. Although a response to treatment with antiviral medications can improve these outcomes, not all patients tolerate these medications or experience viral eradication. Avoiding reinfection of the graft is the most effective means of improving the long-term outcomes for these patient populations. This review is focused on the prevention of viral hepatitis reinfection after liver transplantation. Liver Transpl, 2012. (C) 2012 AASLD.
引用
收藏
页码:514 / 523
页数:10
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