Frequent PIK3R1 somatic mutations in cancer promotes survival signaling

被引：0
|
作者：
Jaiswal, Bijay [1 ]
Janakiraman, Vasant [1 ]
Seshagiri, Somasekar [1 ]
机构：
[1] Genentech Inc, San Francisco, CA 94080 USA
来源：
CANCER RESEARCH | 2009年 / 69卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3381
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Frequent PIK3R1 somatic mutations promote oncogenic signaling
    Jaiswal, Bijay S.
    Janakiraman, Vasantharajan
    Chaudhuri, Subhra
    Stern, Howard M.
    Kljavin, Noelyn M.
    Wang, Weiru
    Kan, Zhengyan
    Bowman, Krista
    Wu, Jiansheng
    Kaminker, Joshua
    Yue, Peng
    de Sauvage, Frederic J.
    Backer, Jonathan
    Seshagiri, Somasekar
    CANCER RESEARCH, 2010, 70
  • [2] Somatic Mutations of PIK3R1 Promote Gliomagenesis
    Quayle, Steven N.
    Lee, Jennifer Y.
    Cheung, Lydia W. T.
    Ding, Li
    Wiedemeyer, Ruprecht
    Dewan, Robert W.
    Huang-Hobbs, Emmet
    Zhuang, Li
    Wilson, Richard K.
    Ligon, Keith L.
    Mills, Gordon B.
    Cantley, Lewis C.
    Chin, Lynda
    PLOS ONE, 2012, 7 (11):
  • [3] Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
    Li Chen
    Liu Yang
    Ling Yao
    Xia-Ying Kuang
    Wen-Jia Zuo
    Shan Li
    Feng Qiao
    Yi-Rong Liu
    Zhi-Gang Cao
    Shu-Ling Zhou
    Xiao-Yan Zhou
    Wen-Tao Yang
    Jin-Xiu Shi
    Wei Huang
    Xin Hu
    Zhi-Ming Shao
    Nature Communications, 9
  • [4] Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
    Chen, Li
    Yang, Liu
    Yao, Ling
    Kuang, Xia-Ying
    Zuo, Wen-Jia
    Li, Shan
    Qiao, Feng
    Liu, Yi-Rong
    Cao, Zhi-Gang
    Zhou, Shu-Ling
    Zhou, Xiao-Yan
    Yang, Wen-Tao
    Shi, Jin-Xiu
    Huang, Wei
    Hu, Xin
    Shao, Zhi-Ming
    NATURE COMMUNICATIONS, 2018, 9
  • [5] PIK3R1 mutations in SHORT syndrome
    Schroeder, C.
    Riess, A.
    Bonin, M.
    Bauer, P.
    Riess, O.
    Doebler-Neumann, M.
    Wieser, S.
    Moog, U.
    Tzschach, A.
    CLINICAL GENETICS, 2014, 86 (03) : 292 - 294
  • [6] Mutations in PIK3R1 Cause SHORT Syndrome
    Dyment, David A.
    Smith, Amanda C.
    Alcantara, Diana
    Schwartzentruber, Jeremy A.
    Basel-Vanagaite, Lina
    Curry, Cynthia J.
    Temple, I. Karen
    Reardon, William
    Mansour, Sahar
    Haq, Mushfequr R.
    Gilbert, Rodney
    Lehmann, Ordan J.
    Vanstone, Megan R.
    Beaulieu, Chandree L.
    Majewski, Jacek
    Bulman, Dennis E.
    O'Driscoll, Mark
    Boycott, Kym M.
    Innes, A. Micheil
    AMERICAN JOURNAL OF HUMAN GENETICS, 2013, 93 (01) : 158 - 166
  • [7] Targeting therapeutic liabilities engendered by PIK3R1 mutations for cancer treatment
    Cheung, Lydia W. T.
    Mills, Gordon B.
    PHARMACOGENOMICS, 2016, 17 (03) : 297 - 307
  • [8] Overexpression of PIK3R1 promotes hepatocellular carcinoma progression
    Xuejun Ai
    Lei Xiang
    Zhi Huang
    Shi Zhou
    Shuai Zhang
    Tao Zhang
    Tianpeng Jiang
    Biological Research, 51
  • [9] A human immunodeficiency caused by mutations in the PIK3R1 gene
    Deau, Marie-Celine
    Heurtier, Lucie
    Frange, Pierre
    Suarez, Felipe
    Bole-Feysot, Christine
    Nitschke, Patrick
    Cavazzana, Marina
    Picard, Capucine
    Durandy, Anne
    Fischer, Alain
    Kracker, Sven
    JOURNAL OF CLINICAL INVESTIGATION, 2014, 124 (09): : 3923 - 3928
  • [10] Overexpression of PIK3R1 promotes hepatocellular carcinoma progression
    Ai, Xuejun
    Xiang, Lei
    Huang, Zhi
    Zhou, Shi
    Zhang, Shuai
    Zhang, Tao
    Jiang, Tianpeng
    BIOLOGICAL RESEARCH, 2018, 51
12345