Anti-contractile and anti-proliferative responses in hum pulmonary arterial smooth muscle cells induced by ACT-333679, the active metabolite of selexipag, a non-prostanoid selective prostacyclin receptor agonist

被引:0
|
作者
Gatfield, John
Menyhart, Katalin
Nayler, Oliver
机构
关键词
Pulmonary hypertension; Cell biology; Pharmacology;
D O I
暂无
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
P2353
引用
收藏
页数:4
相关论文
共 3 条
  • [1] THE NON-PROSTANOID PROSTACYCLIN RECEPTOR AGONIST ACT-333679, THE ACTIVE METABOLITE OF SELEXIPAG, IS CHARACTERIZED BY LOW BETA-ARRESTIN RECRUITMENT AND RECEPTOR INTERNALIZATION ACTIVITY
    Gatfield, John
    Menyhart, Katalin
    Morrison, Keith
    Nayler, Oliver
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 65 (10) : A1542 - A1542
  • [2] Prostanoid EP2 Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells
    Patel, Jigisha A.
    Shen, Lei
    Hall, Susan M.
    Benyahia, Chabha
    Norel, Xavier
    McAnulty, Robin J.
    Moledina, Shahin
    Silverstein, Adam M.
    Whittle, Brendan J.
    Clapp, Lucie H.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (08)
  • [3] Epigenetic Regulation Of The Anti-Proliferative Transient Receptor Potential Melastatin 8 (trpm8) Channels Of Pulmonary Arterial Smooth Muscle Cells In Hypoxic Pulmonary Hypertension
    Sham, J. S. K.
    Paudel, O.
    Tang, W. -Y.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193