Diagnosis of sepsis and guidance of antibiotic therapy

被引:4
|
作者
Oppert, M. [1 ]
机构
[1] Klinikum Ernst von Bergmann, Klin Notfall & Intens Med, Charlottenstr 72, D-14467 Potsdam, Germany
关键词
Biomarkers; Infection; Sepsis; Antibiotic stewardship; Procalcitonin; SEPTIC SHOCK; PROCALCITONIN;
D O I
10.1007/s00063-019-0570-y
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There is awidespread use of biomarkers in modern intensive care. The potential benefit for the patients is, however, not fully investigated. This paper will discuss biomarkers regarding the diagnosis of infections and their potential use in antibiotic stewardship programs (ABS) in order to guide antimicrobial therapy. In the field of infections, procalcitonin (PCT) seems to be the most widespread marker. PCT is able to differentiate between inflammation and infection. Also, in the context of ABS rounds, PCT is well established.
引用
收藏
页码:286 / 289
页数:4
相关论文
共 50 条
  • [1] Sepsisdiagnostik und AntibiotikasteuerungDiagnosis of sepsis and guidance of antibiotic therapy
    M. Oppert
    Medizinische Klinik - Intensivmedizin und Notfallmedizin, 2019, 114 : 286 - 289
  • [2] Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy
    Anders Perner
    Anthony C. Gordon
    Daniel De Backer
    George Dimopoulos
    James A. Russell
    Jeffrey Lipman
    Jens-Ulrik Jensen
    John Myburgh
    Mervyn Singer
    Rinaldo Bellomo
    Timothy Walsh
    Intensive Care Medicine, 2016, 42 : 1958 - 1969
  • [3] Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy
    Perner, Anders
    Gordon, Anthony C.
    De Backer, Daniel
    Dimopoulos, George
    Russell, James A.
    Lipman, Jeffrey
    Jensen, Jens-Ulrik
    Myburgh, John
    Singer, Mervyn
    Bellomo, Rinaldo
    Walsh, Timothy
    INTENSIVE CARE MEDICINE, 2016, 42 (12) : 1958 - 1969
  • [4] Procalcitonin in clinical practice: from diagnosis of sepsis to antibiotic therapy
    Cioni, Gabriele
    Canini, Jessica
    Pieralli, Filippo
    ITALIAN JOURNAL OF MEDICINE, 2021, 15 (01) : 7 - 16
  • [5] Procalcitonin for guidance of antibiotic therapy
    Schuetz, Philipp
    Albrich, Werner
    Christ-Crain, Mirjam
    Chastre, Jean
    Mueller, Beat
    EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2010, 8 (05) : 575 - 587
  • [6] Sepsis management - antibiotic therapy
    Welte, T
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2004, 129 (48) : 2609 - 2613
  • [7] Empirical choice of antibiotic therapy in sepsis
    Finch, RG
    JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF LONDON, 2000, 34 (06): : 528 - 532
  • [8] THE INFLUENCE OF INTRAPARTUM ANTIBIOTIC THERAPY ON THE DIAGNOSIS OF EARLY-ONSET NEONATAL SEPSIS 1338
    RENATO S PROCIANOY
    RITA S VIEIRA
    Pediatric Research, 1997, 41 (Suppl 4) : 225 - 225
  • [9] CLINICAL EVALUATION OF LABORATORY GUIDANCE TO ANTIBIOTIC THERAPY
    ISENBERG, HD
    HEALTH LABORATORY SCIENCE, 1967, 4 (03) : 166 - &
  • [10] Validation of serum C-reactive protein for the diagnosis and monitoring of antibiotic therapy in neonatal sepsis
    Ahmed, Ejaz
    Rehman, Abdur
    Ali, Muhammad Asghar
    PAKISTAN JOURNAL OF MEDICAL SCIENCES, 2017, 33 (06) : 1434 - 1437