Genetic and genomic prospects for Xenopus tropicalis research

被引：24
|
作者：
Carruthers, S [1 ]
Stemple, DL [1 ]
机构：
[1] Sanger Inst, Cambridge CB10 1HH, England
来源：
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2006年 / 17卷 / 01期
基金：
英国惠康基金;
关键词：
Xenopus laevis; Xenopus tropcalis; genetic; mutant;
D O I：
10.1016/j.semcdb.2005.11.009
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Research using Xenopus laevis has made enormous contributions to our understanding of vertebrate development, control of the eukaryotic cell cycle and the cytoskeleton. One limitation, however, has been the lack of systematic genetic studies in Xenopus to complement molecular and cell biological investigations. Work with the closely related diploid frog Xenopus tropicalis is beginning to address this limitation. Here, we review the resources that will make genetic studies using X. tropicalis a reality. (C) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：146 / 153
页数：8
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