Friedel-Crafts Type Methylation with Dimethylhalonium Salts

被引：6

作者：

Haemmerling, Sebastian ^{[1
]}

Vossnacker, Patrick ^{[1
]}

Steinhauer, Simon ^{[1
]}

Beckers, Helmut ^{[1
]}

Riedel, Sebastian ^{[1
]}

机构：

[1] Free Univ Berlin, Inst Chem & Biochem, Fabeckstr 34-36, D-14195 Berlin, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2020年 / 26卷 / 63期

关键词：

electrophilic substitution; halonium ions; methylation; reaction mechanism; weakly coordinating anion; NUCLEAR-MAGNETIC-RESONANCE; SPIN COUPLING-CONSTANTS; BASIS-SETS; PERTURBATION-THEORY; DFT; THERMOCHEMISTRY; STABILITY; SOLVENTS; KINETICS; SOPPA;

D O I：

10.1002/chem.202001457

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The dimethylchloronium salt [Me2Cl][Al(OTeF5)(4)] is used to methylate electron-deficient aromatic systems in Friedel-Crafts type reactions as shown by the synthesis ofN-methylated cations, such as [MeNC5F5](+), [MeNC5F4I](+), and [MeN3C3F3](+). To gain a better understanding of such fundamental Friedel-Crafts reactions, the role of the dimethylchloronium cation has been evaluated by quantum-chemical calculations.

引用

页码：14377 / 14384

页数：8

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